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利用智能医疗大数据分析影响 PKPP 手术并发症发生率的不同相关因素

Different Associated Aspects That Influence Complication Rates on Clinical PKP Surgery Using Smart Medical Big Data.

机构信息

Department of Spinal Orthopedics, General Hospital of Ningxia Medical University, Yinchuan 750000, China.

The Third People's Hospital of Ningxia Hui Autonomous Region, Yinchuan 750000, China.

出版信息

J Healthc Eng. 2022 Mar 21;2022:8432360. doi: 10.1155/2022/8432360. eCollection 2022.

DOI:10.1155/2022/8432360
PMID:35356609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8959986/
Abstract

Osteoporotic vertebral compression fractures are on the rise in modern society due to the aging population, and this often results in painful symptoms and kyphotic abnormalities in patients. Bone cement was injected into the vertebral body to reinforce the vertebral body and restore most of the damaged vertebrae's natural height. Percutaneous kyphoplasty is the name given to this type of procedure (PKP). Bone cement leakage has been linked to several problems, according to the research. Neurological problems might arise if bone cement leaks into the spinal canal or the nerve root canal during surgery. As a result, PKP surgeons must now deal with the issue of reducing bone cement leakage. Using smart medical big data, this paper examines a sample of PKP operations and then examines different associated aspects that influence complication rates in order to better advice clinical PKP surgery use. There were 172 vertebral bodies in total in 72 patients receiving PKP surgery at a Chinese hospital that were examined by smart medical big data for vertebral degeneration and fusion. Bone cement leakage and variations in preoperative average anterior vertebral column height, preoperative Cobb angle, and the volume of injected bone cement were considered when dividing the patients into leakage and nonleakage groups; then, we figure out what is causing the bone cement to leak. Five patients experienced lung-related problems out of the 18 vertebral bodies with bone cement leaking that were selected for study. That leakage rate was 10.5%. The differences between the two groups in terms of vertebral compression and bone cement injection were statistically significant based on a single-factor analysis. Bone cement leakage in PKP surgery has been linked to the amount of bone cement injected and whether the vertebral body's peripheral wall was injured, according to multivariate analysis. Lung-related problems are more common in patients with a prior history of illness. Osteoporotic vertebral compression fractures can be successfully treated with percutaneous kyphoplasty. An important risk factor for bone cement extravasation in PKP surgery is the amount of bone cement injected, as well as its viscosity and whether damage to the vertebral body's peripheral wall has occurred.

摘要

骨质疏松性椎体压缩性骨折在现代社会由于人口老龄化而呈上升趋势,这往往导致患者出现疼痛症状和后凸畸形。向椎体注入骨水泥以增强椎体并恢复大部分受损椎体的自然高度。经皮椎体后凸成形术(PKP)就是这种手术的名称。根据研究,骨水泥渗漏与几个问题有关。如果在手术过程中骨水泥漏入椎管或神经根管,可能会出现神经问题。因此,PKP 外科医生现在必须解决减少骨水泥渗漏的问题。本文利用智能医疗大数据,对一组 PKP 手术进行了检查,然后研究了不同的相关方面,这些方面会影响并发症的发生率,以便更好地为临床 PKP 手术提供建议。在中国的一家医院,对 72 名接受 PKP 手术的患者的 172 个椎体进行了智能医疗大数据检查,以检查椎体退变和融合情况。在将患者分为渗漏组和非渗漏组时,考虑了骨水泥渗漏和术前平均前柱高度、术前 Cobb 角以及注入骨水泥的体积的变化;然后,我们找出导致骨水泥渗漏的原因。在选择进行研究的 18 个骨水泥渗漏椎体中,有 5 例出现了与肺部相关的问题。渗漏率为 10.5%。根据单因素分析,两组在椎体压缩和骨水泥注射方面存在统计学差异。根据多因素分析,PKP 手术中的骨水泥渗漏与注入的骨水泥量以及椎体外周壁是否受损有关。有既往病史的患者更容易出现肺部相关问题。经皮椎体后凸成形术可成功治疗骨质疏松性椎体压缩性骨折。PKP 手术中骨水泥外渗的一个重要危险因素是注入的骨水泥量及其粘性,以及椎体外周壁是否受损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/b1c7dca6d172/JHE2022-8432360.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/ac7910181fb0/JHE2022-8432360.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/c54c80f11ab5/JHE2022-8432360.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/212d99615ae9/JHE2022-8432360.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/28d92e1f133e/JHE2022-8432360.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/b1c7dca6d172/JHE2022-8432360.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/ac7910181fb0/JHE2022-8432360.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/c54c80f11ab5/JHE2022-8432360.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/212d99615ae9/JHE2022-8432360.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/28d92e1f133e/JHE2022-8432360.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8211/8959986/b1c7dca6d172/JHE2022-8432360.008.jpg

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