平面手性1,3-二取代二茂铁基膦金（I）催化剂

Planar Chiral 1,3-Disubstituted Ferrocenyl Phosphine Gold(I) Catalysts.

作者信息

Caniparoli Ulysse, Escofet Imma, Echavarren Antonio M

机构信息

Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007 Tarragona, Spain.

Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, C/Marcel·lí Domingo s/n, 43007 Tarragona, Spain.

出版信息

ACS Catal. 2022 Mar 18;12(6):3317-3322. doi: 10.1021/acscatal.1c05827. Epub 2022 Feb 25.

Planar chiral monodentate 1,3-disubstituted ferrocene phosphines inspired on JohnPhos-type ligands have been synthesized and applied to the enantioselective gold(I) catalyzed [4 + 2] cycloaddition of 1,6-arylenynes. Computational studies rationalized the working mode of the catalyst on the folding of the substrate in the chiral environment of the ligand involving attractive noncovalent interactions.