Australian Centre for the Prevention of Cervical Cancer, Melbourne, Victoria.
National Centre for Immunisation Research and Surveillance, Sydney, New South Wales.
Aust N Z J Public Health. 2022 Jun;46(3):394-400. doi: 10.1111/1753-6405.13233. Epub 2022 Mar 31.
To compare Australian Immunisation Register (AIR) human papillomavirus (HPV) vaccination coverage against historical data from the former National HPV Vaccination Program Register and estimate two-dose vaccination coverage.
Cross-sectional analysis of registry data for adolescent birth cohorts (1998-2007). Denominator populations were Medicare enrolments (AIR) and ABS estimated resident populations (HPV register).
For adolescents aged <17 years, AIR coverage estimates were several percentage points lower than HPV register estimates due to a larger Medicare enrolment denominator. Completed course coverage (two or three valid doses) for 15-year-old females in 2020 was 81.5% and for males 78.6%, higher than completed course coverage in 15-year-olds in 2019 (79.7 and 76.8% respectively). First dose coverage was similar for Indigenous adolescents but course completion was lower, although improving over time. Course completion was slightly lower (3.5-5.7%) in areas of lowest socioeconomic status and greatest remoteness.
Coverage is slightly lower using AIR than HPV register estimates. Moving from three to two doses has slightly improved completion, likely due to the wider dose spacing, but equity gaps remain.
An ongoing focus on equity in vaccine delivery is needed. Systems, reminders and catch-up opportunities to ensure course completion remain important.
比较澳大利亚免疫登记处（AIR）人乳头瘤病毒（HPV）疫苗接种覆盖率与前国家 HPV 疫苗接种计划登记处的历史数据，并估计两剂疫苗接种覆盖率。
对青少年出生队列（1998-2007 年）的登记数据进行横断面分析。分母人群为医疗保险登记（AIR）和 ABS 估计的常住居民人口（HPV 登记处）。
对于<17 岁的青少年，AIR 覆盖率估计值比 HPV 登记处的估计值低几个百分点，这是由于医疗保险登记的分母更大。2020 年，15 岁女性的完整疗程（两剂或三剂有效剂量）覆盖率为 81.5%，男性为 78.6%，高于 2019 年 15 岁儿童的完整疗程覆盖率（分别为 79.7%和 76.8%）。原住民青少年的第一剂覆盖率相似，但课程完成率较低，尽管随着时间的推移有所提高。在社会经济地位最低和最偏远的地区，课程完成率略低（3.5-5.7%）。
使用 AIR 比 HPV 登记处的估计值略低。从三剂改为两剂略微提高了完成率，可能是由于剂量间隔更广，但公平性差距仍然存在。
需要持续关注疫苗接种的公平性。系统、提醒和追赶机会以确保完成课程仍然很重要。
