Hull Brynley, Hendry Alexandra, Dey Aditi, Brotherton Julia, Macartney Kristine, Beard Frank
National Centre for Immunisation Research and Surveillance. The Children's Hospital at Westmead and The University of Sydney.
Commun Dis Intell (2018). 2023 Aug 24;47. doi: 10.33321/cdi.2023.47.47.
We analysed Australian Immunisation Register (AIR) data as at 3 April 2022 for children, adolescents and adults for the calendar year 2021, with data on trends from previous years also presented.
'Fully vaccinated' coverage in Australian children in 2021 was 0.6-0.8 of a percentage point lower than in 2020 at the 12-month (94.2%) and 60-month (94.0%) age assessment milestones, but stable at the 24-month milestone (92.1%). Due to the lag time involved in assessment at milestone ages, 'fully vaccinated' coverage figures for 2020 and 2021 predominantly reflect vaccinations due in 2019 and 2020, respectively, and hence show a small impact on childhood coverage in the first year of the coronavirus disease 2019 (COVID-19) pandemic. 'Fully vaccinated' coverage in Aboriginal and Torres Strait Islander (hereafter respectfully referred to as Indigenous) children was 0.7-1.5 percentage points lower in 2021 than 2020 at the 12-month (91.6%), 24-month (90.1%) and 60-month (96.3%) milestones, although 2.3 percentage points higher than children overall at 60 months. Influenza vaccination coverage in children aged 6-59 months was approximately 20 percentage points lower in 2021 than 2020, both for children overall (26.5%) and for Indigenous children (22.5%). 'On time' vaccination (within 30 days of the recommended age) was up to two percentage points lower in 2021 than 2020 for vaccines due at 4 and 6 months of age, suggesting possible pandemic impacts, but was similar or higher for vaccines due at 12 months of age. While on-time vaccination in Indigenous children has improved progressively since 2012, it remained 6-13 percentage points lower than in children overall in 2021. 'Fully vaccinated' coverage at the earlier milestones (3 months after due date of last scheduled vaccine) of 9, 15, 21 and 51 months was 1.5-2.8 percentage points lower for children living in the least advantaged residential area quintile than the most advantaged, a similar disparity as in 2020. Coverage at the earlier milestones was 2.3-10.0 percentage points lower for Indigenous children living in remote areas than in major cities and regional areas, with disparity at 21 months of age 2.1-2.2 percentage points higher in 2021 than in 2020, and 1.2-2.1 percentage points higher at 51 months.
In 2021, a total of 80.3% of girls and 77.2% of boys (and 73.3% and 66.2% of Indigenous girls and boys) had completed the human papillomavirus (HPV) vaccination schedule by 15 years of age, 0.2-0.4 of a percentage point lower than 2020 (1.7-1.8 percentage points for Indigenous), reflecting vaccinations due in school programs prior to the pandemic with possible pandemic impact on catch-up vaccination. However, the proportion of adolescents completing the two-dose HPV vaccination schedule within a calendar year was 15.3 percentage points lower in 2021 than 2020 and 26.9 percentage points lower than in 2019, likely due to pandemic-related disruption to school-based programs. Additionally, 87.3% of adolescents (83.8% for Indigenous) had received the recommended booster dose of diphtheria-tetanus-acellular pertussis (dTpa) vaccine by 15 years, and 76.1% (66.7% for Indigenous) the recommended meningococcal ACWY vaccine dose by 17 years of age.
Zoster vaccine coverage in 2021 remained relatively low, at just over 30%, in adults aged 70 years, but increased to 47% in those aged 71-79 years, reflecting ongoing catch-up vaccination. Coverage of 13vPCV was low in 2021, reaching 17.2% in adults aged 70 years and 20.1% in those aged 71-79 years. Influenza vaccination coverage in adults in 2021 was progressively higher with increasing age, reaching 62.1% in the 65-74 years age group (64.6% in Indigenous) and 68.5% in the 75+ years age group (67.7% in Indigenous). Influenza vaccine coverage for other National Immunisation Program (NIP)-eligible Indigenous adult age groups was only 22.0% for those aged 20-49 years, and 43.5% for those aged 50-64 years. By the end of 2021, a total of 91.6% of people in Australia aged 16+ years had received a second dose of a COVID-19 vaccine (71.8% for Indigenous), with over 99% of those aged 70+ years having received a second dose.
Vaccination coverage in children and adolescents remained relatively high in 2021, although with some evidence of COVID-19 pandemic impacts, particularly on receipt of two doses of HPV vaccine within the same calendar year. It will be important to ensure catch-up vaccination in children and adolescents occurs. A strengthened focus on adult vaccination is needed, as coverage remained suboptimal in 2021. The impact of mandatory reporting of all NIP vaccinations from mid-2021, on completeness of AIR data, has not yet been formally evaluated.
我们分析了截至2022年4月3日澳大利亚免疫接种登记册(AIR)中2021历年儿童、青少年及成人的数据,并呈现了往年的趋势数据。
2021年澳大利亚儿童在12个月(94.2%)和60个月(94.0%)年龄评估节点的“全程接种”覆盖率比2020年低0.6 - 0.8个百分点,但在24个月节点(92.1%)保持稳定。由于在各年龄节点进行评估存在滞后时间,2020年和2021年的“全程接种”覆盖率数据主要分别反映2019年和2020年应接种的疫苗,因此显示出2019冠状病毒病(COVID - 19)大流行第一年对儿童接种覆盖率的影响较小。2021年,原住民和托雷斯海峡岛民(以下简称原住民)儿童在12个月(91.6%)、24个月(90.1%)和60个月(96.3%)节点的“全程接种”覆盖率比2020年低0.7 - 1.5个百分点,不过在60个月时比所有儿童总体高2.3个百分点。2021年,6 - 59个月儿童的流感疫苗接种覆盖率,所有儿童总体(26.5%)和原住民儿童(22.5%)均比2020年低约20个百分点。2021年,4个月和6个月龄应接种疫苗的“及时接种”(在推荐年龄的30天内)比2020年低达2个百分点,表明可能受到大流行影响,但12个月龄应接种疫苗的及时接种率与之相似或更高。尽管自2012年以来原住民儿童的及时接种情况逐步改善,但2021年仍比所有儿童总体低6 - 13个百分点。在9、15、21和51个月等较早节点(最后一剂预定疫苗到期日期后3个月),生活在最不利居住区五分之一的儿童“全程接种”覆盖率比最有利的儿童低1.5 - 2.8个百分点,与2020年的差距相似。居住在偏远地区的原住民儿童在较早节点的覆盖率比主要城市和地区低2.3 - 10.0个百分点,21个月龄时的差距在2021年比2020年高2.1 - 2.2个百分点,51个月龄时高1.2 - 2.1个百分点。
2021年,共有80.3%的女孩和77.2%的男孩(原住民女孩和男孩分别为73.3%和66.2%)在15岁前完成了人乳头瘤病毒(HPV)疫苗接种程序,比2020年低0.2 - 0.4个百分点(原住民低1.7 - 1.8个百分点),这反映了大流行前学校项目中应接种的疫苗以及大流行可能对补种疫苗产生的影响。然而,202年1青少年在一个日历年内完成两剂HPV疫苗接种程序的比例比2020年低15.3个百分点,比2019年低26.9个百分点,这可能是由于与大流行相关的学校项目中断所致。此外,87.3%的青少年(原住民为83.8%)在15岁前接种了推荐的白喉 - 破伤风 - 无细胞百日咳(dTpa)疫苗加强剂,76.1%(原住民为66.7%)在年满17岁前接种了推荐的A、C、W、Y群脑膜炎球菌疫苗。
2021年,70岁成人的带状疱疹疫苗接种覆盖率仍然相对较低,略高于30%,但71 - 岁成人的覆盖率升至47%,这反映了持续的补种接种情况。2021年13价肺炎球菌结合疫苗(13vPCV)的接种覆盖率较低,70岁成人中达到17.2%,71 - 79岁成人中达到20.1%。2021年成人流感疫苗接种覆盖率随年龄增长逐渐升高,65 - 74岁年龄组达到62.1%(原住民为64.6%),75岁及以上年龄组达到68.5%(原住民为67.7%)。其他符合国家免疫规划(NIP)的原住民成人年龄组的流感疫苗接种覆盖率,20 - 49岁年龄组仅为22.0%,50 - 64岁年龄组为43.5%。截至2021年底,澳大利亚16岁及以上人群中共有91.6%接种了第二剂COVID - 19疫苗(原住民为71.8%),70岁及以上人群中超过99%接种了第二剂。
2021年儿童和青少年的疫苗接种覆盖率仍然相对较高,尽管有一些证据表明受到了COVID - 19大流行的影响,特别是在同一年内接种两剂HPV疫苗方面。确保儿童和青少年进行补种疫苗将很重要。需要加强对成人疫苗接种的关注,因为2021年的接种覆盖率仍未达到最佳水平。2021年年中开始强制报告所有NIP疫苗接种情况对AIR数据完整性的影响尚未得到正式评估。