Department of Diabetes and Endocrinology, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.
Diabet Med. 2022 Jul;39(7):e14838. doi: 10.1111/dme.14838. Epub 2022 Apr 8.
Perioperative diabetes management has become increasingly complex; management is often inconsistent resulting in dysglycaemia and associated morbidity.
To evaluate a structured pre-admission perioperative diabetes management plan (PDMP) for safe and appropriate recommendation, prescription and administration of diabetes medications in the perioperative period for people with diabetes undergoing elective, non-cardiac surgery.
A multidisciplinary team developed the intervention, a structured PDMP (including diabetes medication reconciliation, management guide, individualised plan) to standardise optimal perioperative diabetes management. A single centre prospective pre- and post-intervention pilot study was performed, including all individuals with diabetes medications attending the pre-admissions clinic during two 4-month periods (February to May) in 2016 (control period) and 2017 (intervention period). The primary outcome was appropriate recommendation, prescription and administration of diabetes medications (including insulin), according to the PDMP, in the perioperative period. Secondary outcomes measures were glycaemia. Analysis was by intention to treat.
Control and intervention groups included 131 and 133 participants, respectively; they were well matched in clinical characteristics. The PDMP was completed correctly in 100 (75%) individuals in the intervention group. The appropriate use of diabetes medications increased from 30% in the control group to 71% in the intervention group (p < 0.001). Following the PDMP implementations, glycaemia improved in the overall perioperative period (8.7 ± 2.9 vs. 9.8 ± 3.3 mmol/L, p = 0.005) and at all time points (from admission and over entire hospital stay).
A structured pre-admission perioperative diabetes management plan for elective surgery improved safe and appropriate diabetes medication use and glycaemia in the perioperative period.
围手术期的糖尿病管理变得越来越复杂;管理通常不一致,导致血糖控制不佳和相关发病率增加。
评估一种结构化的术前围手术期糖尿病管理计划(PDMP),以安全和适当的方式推荐、开具和管理接受择期非心脏手术的糖尿病患者的围手术期糖尿病药物。
一个多学科团队开发了该干预措施,即一种结构化的 PDMP(包括糖尿病药物重整、管理指南、个体化计划),以标准化最佳围手术期糖尿病管理。在 2016 年 2 月至 5 月的两个 4 个月期间(对照期)和 2017 年(干预期),在术前门诊就诊的所有使用糖尿病药物的个体中进行了一项单中心前瞻性干预前后试点研究。主要结局是根据 PDMP 在围手术期适当推荐、开具和管理糖尿病药物(包括胰岛素)。次要结局措施是血糖。分析采用意向治疗。
对照组和干预组分别纳入了 131 名和 133 名参与者,两组在临床特征上具有良好的可比性。在干预组中,有 100 名(75%)个体正确完成了 PDMP。糖尿病药物的合理使用从对照组的 30%增加到干预组的 71%(p<0.001)。实施 PDMP 后,整个围手术期的血糖水平有所改善(8.7±2.9 与 9.8±3.3mmol/L,p=0.005),且所有时间点(从入院到整个住院期间)均如此。
对于择期手术,结构化的术前围手术期糖尿病管理计划可改善围手术期安全和适当的糖尿病药物使用和血糖控制。