Neuroscience Program.
Behav Neurosci. 2022 Aug;136(4):293-299. doi: 10.1037/bne0000514. Epub 2022 Mar 31.
Serotonin is an important modulator of feeding behavior across animal species. In invertebrates, much is known about the regulation of feeding in several model organisms, but comparative data are limited. We examined the modulation of feeding behavior in crayfish by administering serotonin and two serotonin receptor ligands, mianserin and 5-carboxamidotryptamine. We found that, compared to control injections, exogenous serotonin significantly reduced appetitive behaviors in response to a chemical food stimulant and reduced consumption when food was present. The two ligands also significantly reduced the amount of food consumed. However, they had no significant effects on appetitive feeding movements, suggesting that appetitive and consummatory feeding phases may be regulated by different serotonergic mechanisms. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
血清素是调节动物物种摄食行为的重要调质。在无脊椎动物中，人们对几种模式生物的摄食调控有了较多的了解，但比较数据有限。我们通过给螯虾注射血清素和两种血清素受体配体米氮平和 5-羧基色胺来研究其摄食行为的调制。结果发现，与对照注射相比，外源性血清素显著降低了对化学食物刺激的摄食行为反应，并在有食物存在时减少了摄食量。两种配体也显著减少了食物的消耗量。然而，它们对摄食运动没有显著影响，这表明摄食和饱食阶段可能受到不同的血清素能机制的调节。（PsycInfo 数据库记录（c）2022 APA，保留所有权利）。
