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鼻腔孤立性纤维瘤:一例报告并文献复习

Solitary Fibrous tumor of Nasal cavity: A case report and review of literature.

作者信息

Khribi Mayssa, Wassim Kermani, Abir Meherzi, Sriha Badreddine, Bellakhdhar Mouna, Abdelkefi Mohamed

机构信息

University of Sousse, Faculty of Medicine of Sousse, ENT Department, Farhat Hached Teaching Hospital, Sousse, Tunisia.

University of Sousse, Faculty of Medicine of Sousse, ENT Department, Farhat Hached Teaching Hospital, Sousse, Tunisia.

出版信息

Int J Surg Case Rep. 2022 Apr;93:106950. doi: 10.1016/j.ijscr.2022.106950. Epub 2022 Mar 16.

Abstract

INTRODUCTION AND IMPORTANCE

Solitary fibrous tumors (SFTs) involving the nasal cavity are extremely rare with few cases reported in the literature.

CASE PRESENTATION

We present a case of SFT in a 90 year-old male complaining of a slow-growing mass prolapsing through left nostril. Nasal endoscopy and imaging exams revealed a mass occupying the entire left nasal cavity, pushing the nasal septum to the opposite side and extending up to the nasopharynx. Biopsy specimen examination reported sarcoma. The patient underwent complete surgical resection of the mass through left para-latero-nasal approach. Immuno-histochemical analyses confirmed the diagnosis of SFT. The patient has remained free of tumor 2 years after surgery.

CLINICAL DISCUSSION

Clinical and imaging features of SFTs of nasal cavity are not specific. A broad of differential diagnosis is associated with histopathologic features of SFTs. Therefore, immuno-histochemical analyses are crucial to confirm the diagnosis. Complete resection of the mass with clear margins is mandatory to minimize local recurrence.

CONCLUSION

SFTs of nasal cavity are very rare neoplasms which continue to pose challenges to practitioner. Pathological examination and mainly immunohistochemical studies are important to establish the diagnosis. Complete resection of the tumor is the key for good outcome.

摘要

引言与重要性

累及鼻腔的孤立性纤维瘤(SFTs)极为罕见,文献报道的病例很少。

病例介绍

我们报告一例90岁男性的SFT病例,患者主诉左侧鼻孔有一生长缓慢的肿物脱出。鼻内镜检查和影像学检查显示肿物占据整个左侧鼻腔,将鼻中隔推向对侧并延伸至鼻咽部。活检标本检查报告为肉瘤。患者通过左侧鼻旁外侧入路接受了肿物的完整手术切除。免疫组织化学分析确诊为SFT。术后2年患者无肿瘤复发。

临床讨论

鼻腔SFT的临床和影像学特征不具有特异性。广泛的鉴别诊断与SFT的组织病理学特征相关。因此,免疫组织化学分析对于确诊至关重要。完整切除肿物且切缘清晰是减少局部复发的必要条件。

结论

鼻腔SFT是非常罕见的肿瘤,仍然给从业者带来挑战。病理检查,主要是免疫组织化学研究对于确诊很重要。完整切除肿瘤是取得良好预后的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fca/8968015/322ba7a8c3f5/gr1.jpg

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