• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[关于扩大慢性乙型肝炎抗乙肝病毒治疗的专家意见]

[Expert opinion on expanding anti-HBV treatment for chronic hepatitis B].

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2022 Feb 20;30(2):131-136. doi: 10.3760/cma.j.cn501113-20220209-00060.

DOI:10.3760/cma.j.cn501113-20220209-00060
PMID:35359064
Abstract

To meet the unmet medical needs and better reflect the new clinical evidence of chronic hepatitis B management, Chinese Society of Hepatology developed expert consensus on expanding diagnosis and treatment in China. The recommendations include to expand HBsAg screening in the population and HBV DNA detection by sensitive quantitative real-time PCR (qPCR), decrease the alanine aminotransferase (ALT) threshold for treatment of chronic hepatitis B, and promptly start antiviral therapy in the patients who are at risk of disease progression, and appropriately manage the patients with low level viremia.

摘要

为满足未被满足的医疗需求并更好地反映慢性乙型肝炎管理的新临床证据,中华医学会肝病学分会制定了中国扩大慢性乙型肝炎诊断和治疗的专家共识。建议包括扩大人群中HBsAg筛查及采用灵敏的定量实时PCR(qPCR)检测HBV DNA,降低慢性乙型肝炎治疗的丙氨酸氨基转移酶(ALT)阈值,对有疾病进展风险的患者及时启动抗病毒治疗,并对低病毒血症患者进行适当管理。

相似文献

1
[Expert opinion on expanding anti-HBV treatment for chronic hepatitis B].[关于扩大慢性乙型肝炎抗乙肝病毒治疗的专家意见]
Zhonghua Gan Zang Bing Za Zhi. 2022 Feb 20;30(2):131-136. doi: 10.3760/cma.j.cn501113-20220209-00060.
2
Application strategies of serum HBV DNA detection in HBV infection patients: A retrospective study of 5611 specimens.HBV 感染患者血清 HBV DNA 检测的应用策略:5611 例标本的回顾性研究。
J Med Virol. 2019 Feb;91(2):249-257. doi: 10.1002/jmv.25271. Epub 2018 Nov 2.
3
Hepatitis B surface antigen loss and sustained viral suppression in Asian chronic hepatitis B patients: A community-based real-world study.亚洲慢性乙型肝炎患者的乙肝表面抗原消失和持续病毒抑制:一项基于社区的真实世界研究。
J Viral Hepat. 2017 Dec;24(12):1089-1097. doi: 10.1111/jvh.12736. Epub 2017 Jul 29.
4
[Analysis of the clinical characteristics of HBeAg-negative chronic HBV infection in indeterminate phase with a low viral load].低病毒载量不确定期HBeAg阴性慢性HBV感染的临床特征分析
Zhonghua Gan Zang Bing Za Zhi. 2024 Nov 20;32(11):970-975. doi: 10.3760/cma.j.cn501113-20231028-00158.
5
ALT to qHBsAg ratio predicts long-term HBsAg seroclearance after entecavir cessation in Chinese patients with chronic hepatitis B.ALT 与 qHBsAg 比值可预测中国慢性乙型肝炎患者恩替卡韦停药后 HBsAg 长期清除。
J Hepatol. 2024 Aug;81(2):218-226. doi: 10.1016/j.jhep.2024.03.022. Epub 2024 Mar 26.
6
The importance of the serum quantitative levels of hepatitis B surface antigen and hepatitis B e antigen in children with chronic hepatitis B.慢性乙型肝炎患儿血清乙型肝炎表面抗原和乙型肝炎e抗原定量水平的重要性。
Turk J Gastroenterol. 2015 Jan;26(1):36-41. doi: 10.5152/tjg.2015.4636.
7
The Study of Clinical and Biochemical Parameters in Assessing the Response to the Antiviral Therapy in the Chronic Viral Hepatitis B.评估慢性乙型病毒性肝炎抗病毒治疗应答的临床和生化参数研究。
Medicina (Kaunas). 2021 Jul 26;57(8):757. doi: 10.3390/medicina57080757.
8
Clinical evaluation and applications of the Amplicor HBV Monitor test, a quantitative HBV DNA PCR assay.Amplicor HBV监测检测(一种定量HBV DNA聚合酶链反应检测法)的临床评估及应用
J Virol Methods. 1998 Oct;74(2):155-65. doi: 10.1016/s0166-0934(98)00081-0.
9
Hepatitis B surface antigen seroclearance in patients with chronic hepatitis B infection: a clinical study.慢性乙型肝炎感染患者的乙肝表面抗原血清学清除:一项临床研究。
J Int Med Res. 2013 Oct;41(5):1732-9. doi: 10.1177/0300060513487643. Epub 2013 Aug 1.
10
Baseline HBsAg levels associated with HBsAg loss in HBeAg-negative chronic hepatitis B infection with persistently normal alanine aminotransferase.基线 HBsAg 水平与持续正常丙氨酸氨基转移酶的 HBeAg 阴性慢性乙型肝炎感染中 HBsAg 丢失相关。
Clin Res Hepatol Gastroenterol. 2019 Jun;43(3):310-316. doi: 10.1016/j.clinre.2018.10.017. Epub 2018 Dec 5.

引用本文的文献

1
Detection technology and clinical applications of serum viral products of hepatitis B virus infection.乙型肝炎病毒感染血清病毒产物的检测技术及其临床应用。
Front Cell Infect Microbiol. 2024 Jul 5;14:1402001. doi: 10.3389/fcimb.2024.1402001. eCollection 2024.
2
"Treat-all" Strategy for Patients with Chronic Hepatitis B Virus Infection in China: Are We There Yet?中国慢性乙型肝炎病毒感染患者的“全面治疗”策略:我们做到了吗?
J Clin Transl Hepatol. 2024 Jun 28;12(6):589-593. doi: 10.14218/JCTH.2024.00091. Epub 2024 May 28.
3
Research advances in serum chitinase-3-like protein 1 in liver fibrosis.
血清壳多糖酶-3样蛋白1在肝纤维化中的研究进展
Front Med (Lausanne). 2024 Jun 19;11:1372434. doi: 10.3389/fmed.2024.1372434. eCollection 2024.
4
Latest insights into the epidemiology, characteristics, and therapeutic strategies of chronic hepatitis B patients in indeterminate phase.慢性乙型肝炎不确定期患者的流行病学、特征和治疗策略的最新见解。
Eur J Med Res. 2024 Jun 21;29(1):343. doi: 10.1186/s40001-024-01942-0.
5
Multimodal imaging-based prediction of recurrence for unresectable HCC after downstage and resection-cohort study.基于多模态影像的不可切除 HCC 降期后复发预测及切除队列研究。
Int J Surg. 2024 Sep 1;110(9):5672-5684. doi: 10.1097/JS9.0000000000001752.
6
High immunocompetence in chronic hepatitis patients with normal alanine transaminase levels and and negative hepatitis B e-antigen for the progression of liver fibrosis.高免疫应答慢性乙型肝炎患者肝纤维化进展的预测因素研究。
Immun Inflamm Dis. 2024 Jan;12(1):e1134. doi: 10.1002/iid3.1134.
7
Tenofovir amibufenamide tenofovir alafenamide for treating chronic hepatitis B: A real-world study.替诺福韦艾米芬酰胺 替诺福韦艾拉酚胺治疗慢性乙型肝炎:一项真实世界研究。
World J Gastroenterol. 2023 Nov 28;29(44):5907-5918. doi: 10.3748/wjg.v29.i44.5907.
8
Lowering the threshold of alanine aminotransferase for enhanced identification of significant hepatic injury in chronic hepatitis B patients.降低丙氨酸氨基转移酶阈值以增强对慢性乙型肝炎患者显著肝损伤的识别
World J Gastroenterol. 2023 Sep 21;29(35):5166-5177. doi: 10.3748/wjg.v29.i35.5166.
9
Guidelines for the Prevention and Treatment of Chronic Hepatitis B (version 2022).《慢性乙型肝炎防治指南(2022年版)》
J Clin Transl Hepatol. 2023 Nov 28;11(6):1425-1442. doi: 10.14218/JCTH.2023.00320. Epub 2023 Aug 15.
10
Clinicopathologic characteristics of liver inflammation and fibrosis in 310 patients with chronic hepatitis B.310 例慢性乙型肝炎患者的肝炎症和纤维化的临床病理特征。
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 May 28;48(5):698-706. doi: 10.11817/j.issn.1672-7347.2023.220622.