Zhonghua Gan Zang Bing Za Zhi. 2022 Feb 20;30(2):131-136. doi: 10.3760/cma.j.cn501113-20220209-00060.
To meet the unmet medical needs and better reflect the new clinical evidence of chronic hepatitis B management, Chinese Society of Hepatology developed expert consensus on expanding diagnosis and treatment in China. The recommendations include to expand HBsAg screening in the population and HBV DNA detection by sensitive quantitative real-time PCR (qPCR), decrease the alanine aminotransferase (ALT) threshold for treatment of chronic hepatitis B, and promptly start antiviral therapy in the patients who are at risk of disease progression, and appropriately manage the patients with low level viremia.
为满足未被满足的医疗需求并更好地反映慢性乙型肝炎管理的新临床证据,中华医学会肝病学分会制定了中国扩大慢性乙型肝炎诊断和治疗的专家共识。建议包括扩大人群中HBsAg筛查及采用灵敏的定量实时PCR(qPCR)检测HBV DNA,降低慢性乙型肝炎治疗的丙氨酸氨基转移酶(ALT)阈值,对有疾病进展风险的患者及时启动抗病毒治疗,并对低病毒血症患者进行适当管理。