Zhonghua Gan Zang Bing Za Zhi. 2022 Feb 20;30(2):159-168. doi: 10.3760/cma.j.cn501113-20220130-00053.
The prognosis of severe liver disease combined with invasive fungal infection (IFI) is poor, and the clinical manifestations are often atypical. Moreover, most of the antifungal drugs are metabolized in the liver, with severe toxicities and side effects, making clinical diagnosis and treatment difficult. The Professional Committee for Hepatology, the Chinese Research Hospital Association and the Hepatology Branch of China Medical Association organized relevant experts to formulate an expert consensus based on the characteristics of patients with severe liver disease combined with IFI, in order to provide reference for medical personnel in making decisions on the diagnosis and treatment.
重症肝病合并侵袭性真菌感染(IFI)的预后较差,且临床表现常不典型。此外,大多数抗真菌药物在肝脏代谢,毒性和副作用严重,给临床诊断和治疗带来困难。中国研究型医院学会肝病专业委员会和中华医学会肝病学分会组织相关专家,根据重症肝病合并IFI患者的特点制定专家共识,为医务人员的诊疗决策提供参考。