Zhonghua Wai Ke Za Zhi. 2022 May 1;60(5):409-423. doi: 10.3760/cma.j.cn112139-20220223-00078.
Organ transplantation is the most effective treatment for end stage organ failure,and voluntary donation after citizen's death is the only source of transplanted organ in China.Clinically,transplantation organ protection technology plays a critical role in improving the quality of transplantation organs and the prognosis of recipients.On the basis of domestic and worldwide basic research and clinical practice and according to the Oxford evidence classification and GRADE system,the experts organized by Organ Transplantation Doctor Branch of Chinese Medical Doctor Association,Organ Transplantation Group in Surgery Branch of Chinese Medical Association and China Liver Transplant Registry Scientific Committee had compiled and published for liver,kidney,pancreas,small intestine,heart,lung transplantation organs.With the support of China Liver Transplant Registry,National Center for Healthcare Quality Management in Liver Transplant,National Quality Control Center for Donated Organ Procurement,National Clinical Research Center for Orthopedics & Sports Medicine & Rehabilitation and National Trauma Medical Organ Protection Committee and combined with recent domestic and worldwide clinical practice and research progress for organ transplantation and organ protection,(hereinafter referred to as the consensus) has been formulated in 2022.This edition of the consensus focuses on updating the technical progress and evidence-based medicine of organ procurement,organ preservation,organ transport,and quality evaluation in clinical practice.Additionally,protection of composite tissue for transplantation,mainly including limb graft,has also been included.The organ protection strategy recommended in this consensus aims to promote scientific and standardize clinical organ transplantation work.
器官移植是终末期器官衰竭最有效的治疗方法,公民逝世后自愿捐献是我国移植器官的唯一来源。临床上,移植器官保护技术对于提高移植器官质量和受者预后起着关键作用。依据国内外基础研究和临床实践,并参照牛津证据分级和GRADE系统,由中华医学会器官移植学分会、中华医学会外科学分会器官移植学组以及中国肝脏移植注册中心科学委员会组织专家编写并发布了肝、肾、胰、小肠、心、肺移植器官相关内容。在中国肝脏移植注册中心、国家肝脏移植质量管理中心、国家人体捐献器官获取质量控制中心、国家骨科与运动医学临床研究中心、国家创伤医学器官保护专业委员会的支持下,结合近期国内外器官移植及器官保护的临床实践与研究进展,于2022年制定了本共识(以下简称共识)。本版共识重点更新了临床实践中器官获取、器官保存、器官运输及质量评估的技术进展和循证医学内容。此外,还纳入了移植复合组织(主要包括肢体移植)的保护内容。本共识推荐的器官保护策略旨在推动临床器官移植工作科学、规范开展。