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关于循环死亡后供体的常温区域灌注的共识声明:来自欧洲器官移植学会移植学习之旅的报告。

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation's Transplant Learning Journey.

机构信息

Transplantation Research Group, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.

Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.

出版信息

Transpl Int. 2021 Nov;34(11):2019-2030. doi: 10.1111/tri.13951.

DOI:10.1111/tri.13951
PMID:34145644
Abstract

Normothermic regional perfusion (NRP) in donation after circulatory death (DCD) is a safe alternative to in situ cooling and rapid procurement. An increasing number of countries and centres are performing NRP, a technically and logistically challenging procedure. This consensus document provides evidence-based recommendations on the use of NRP in uncontrolled and controlled DCDs. It also offers minimal ethical, logistical and technical requirements that form the foundation of a safe and effective NRP programme. The present article is based on evidence and opinions formulated by a panel of European experts of Workstream 04 of the Transplantation Learning Journey project, which is part of the European Society for Organ Transplantation.

摘要

常温区域性灌注(NRP)在循环死亡后捐献(DCD)中是一种安全的替代原位冷却和快速采集的方法。越来越多的国家和中心正在进行 NRP,这是一项技术和后勤方面具有挑战性的程序。本共识文件提供了关于在非控制和控制 DCD 中使用 NRP 的循证建议。它还提供了最低限度的伦理、后勤和技术要求,这些要求构成了安全有效的 NRP 计划的基础。本文基于移植学习之旅项目工作组 04 的欧洲专家小组制定的证据和意见,该项目是欧洲器官移植学会的一部分。

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