Transplantation Research Group, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.
Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.
Transpl Int. 2021 Nov;34(11):2019-2030. doi: 10.1111/tri.13951.
Normothermic regional perfusion (NRP) in donation after circulatory death (DCD) is a safe alternative to in situ cooling and rapid procurement. An increasing number of countries and centres are performing NRP, a technically and logistically challenging procedure. This consensus document provides evidence-based recommendations on the use of NRP in uncontrolled and controlled DCDs. It also offers minimal ethical, logistical and technical requirements that form the foundation of a safe and effective NRP programme. The present article is based on evidence and opinions formulated by a panel of European experts of Workstream 04 of the Transplantation Learning Journey project, which is part of the European Society for Organ Transplantation.
常温区域性灌注(NRP)在循环死亡后捐献(DCD)中是一种安全的替代原位冷却和快速采集的方法。越来越多的国家和中心正在进行 NRP,这是一项技术和后勤方面具有挑战性的程序。本共识文件提供了关于在非控制和控制 DCD 中使用 NRP 的循证建议。它还提供了最低限度的伦理、后勤和技术要求,这些要求构成了安全有效的 NRP 计划的基础。本文基于移植学习之旅项目工作组 04 的欧洲专家小组制定的证据和意见,该项目是欧洲器官移植学会的一部分。