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双极镊夹在肝实质离断中的临床应用

[Clinical application of bipolar tweezers-clamp for hepatic parenchymal transection].

作者信息

Peng S Y, Huang C Y, Zhu L M, Wu W Y, Liu Y, Tan Z X, Ouyang H, Song Hao

机构信息

Department of General Surgery,the Second Affiliate Hospital,Zhejiang University Medical School,Hangzhou 310009,China.

Department of Hepatobiliary Surgery,Yuebei People's Hospital Affiliated to Shantou University Medical College,Shaoguan 512026,China.

出版信息

Zhonghua Wai Ke Za Zhi. 2022 May 1;60(5):449-453. doi: 10.3760/cma.j.cn112139-20210629-00280.

Abstract

To investigate the clinical value of the bipolar tweezers-clamp for the hepatic parenchymal transection in the resection of hepatocellular carcinoma. From January 2020 to January 2021,63 patients with the hepatocellular carcinoma for hepatectomy at Department of Hepatopancreatobiliary Surgery,Yuebei People's Hospital Affiliated to Shantou University Medical College were analyzed retrospectively.According to the different instruments used in the hepatic parenchymal transection,the patients were divided into bipolar tweezers-clamp group and ultrasonic scalpel group.There were 32 patients in bipolar tweezers-clamp group,with age of (55.5±10.5)years(range:37 to 78 years),including 22 males and 10 females,tumor size was (6.0±3.4)cm(range:2.4 to 13.4 cm). There were 6 patients with portal vein tumor thrombus and 5 patients with portal hypertension. There were 31 patients in ultrasonic scalpel group,with aged(57.8±10.1)years(range:37 to 79 years),including 27males and 4 females,tumor size was(7.9±5.1)cm(range: 2.4 to 21.3 cm),3 patients with portal vein tumor thrombus and 2 patients with portal hypertension. The preoperative baseline data,operation time,blood loss,postoperative liver function and the complications were compared between two groups using test,χ test and Fisher exact probabilityrespectively. The operation was successfully completed in both groups.Compared with the ultrasonic scalpel group,the operation time was significantly shorter((219.3±76.4)minutes (294.0±100.8)minutes,=-3.322,0.002),the blood loss was less((250(475)ml 500(1 050)ml=-2.307,0.026),the concentrate red blood cells transfusion volume was less(0.92(0.88)U 2.32(4.00)U,=-1.987,=0.047) in the bipolar tweezers-clamp group.The postoperative serum ALB level was higher in the bipolar tweezers-clamp group than that in the ultrasonic scalpel group((33.5±6.1)g/L (29.5±4.2)g/L,=3.226,=0.020) on postoperative day 1;((35.7±4.5)g/L (30.1±3.2)g/L,=5.575,<0.01) on postoperative day 3;((33.2±3.7)g/L (31.0±4.4)g/L,=3.020,=0.004) on postoperative day 7. There was no significant difference in serum ALT,TBIL and PT level between the two groups(all 0.05).No postoperative bile leakage occurred in both groups.The postoperative complications occurred in 8 cases(25.0%)in the bipolar tweezers-clamp group,including liver failure in one,and in 11 cases(35.5%)in the ultrasonic scalpel group,including liver failure in two(>0.05). The bipolar tweezers-clamp is a safe and reliable method for the hepatic parenchymal transaction,which is quick and less bleeding during the hepatic resection.

摘要

探讨双极镊夹法在肝细胞癌肝切除术中肝实质离断的临床应用价值。回顾性分析2020年1月至2021年1月汕头大学医学院附属粤北人民医院肝胆胰外科收治的63例行肝切除术的肝细胞癌患者的临床资料。根据肝实质离断时使用的器械不同,将患者分为双极镊夹组和超声刀组。双极镊夹组32例,年龄(55.5±10.5)岁(范围:37~78岁),男22例,女10例,肿瘤大小(6.0±3.4)cm(范围:2.4~13.4 cm),门静脉癌栓6例,门静脉高压5例。超声刀组31例,年龄(57.8±10.1)岁(范围:37~79岁),男27例,女4例,肿瘤大小(7.9±5.1)cm(范围:2.4~21.3 cm),门静脉癌栓3例,门静脉高压2例。采用t检验、χ²检验和Fisher确切概率法分别比较两组患者术前基线资料、手术时间、术中出血量、术后肝功能及并发症发生情况。两组手术均顺利完成。与超声刀组比较,双极镊夹组手术时间明显缩短((219.3±76.4)分钟比(294.0±100.8)分钟,t=-3.322,P=0.002),术中出血量少((250(475)ml比500(1 050)ml,t=-2.307,P=0.026),浓缩红细胞输注量少(0.92(0.88)U比2.32(4.00)U,t=-1.987,P=0.047)。术后第1天双极镊夹组血清白蛋白水平高于超声刀组((33.5±6.1)g/L比(29.5±4.2)g/L,t=3.226,P=0.020);术后第3天((35.7±4.5)g/L比(30.1±3.2)g/L,t=5.575,P<0.01);术后第7天((33.2±3.7)g/L比(31.0±4.4)g/L,t=3.020,P=0.004)。两组血清谷丙转氨酶、总胆红素及凝血酶原时间比较,差异均无统计学意义(均P>0.05)。两组均未发生术后胆漏。双极镊夹组术后发生并发症8例(25.0%),其中肝功能衰竭1例;超声刀组术后发生并发症11例(35.5%),其中肝功能衰竭2例(P>0.05)。双极镊夹法是一种安全可靠的肝实质离断方法,肝切除术中操作迅速、出血少。

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