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抗寄生虫药物能帮助控制新冠病毒吗?

Can anti-parasitic drugs help control COVID-19?

作者信息

Panahi Yasin, Dadkhah Masoomeh, Talei Sahand, Gharari Zahra, Asghariazar Vahid, Abdolmaleki Arash, Matin Somayeh, Molaei Soheila

机构信息

Department of Pharmacology & Toxicology, School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran.

Pharmaceutical Sciences Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.

出版信息

Future Virol. 2022 Mar. doi: 10.2217/fvl-2021-0160. Epub 2022 Mar 18.

Abstract

Novel COVID-19 is a public health emergency that poses a serious threat to people worldwide. Given the virus spreading so quickly, novel antiviral medications are desperately needed. Repurposing existing drugs is the first strategy. Anti-parasitic drugs were among the first to be considered as a potential treatment option for this disease. Even though many papers have discussed the efficacy of various anti-parasitic drugs in treating COVID-19 separately, so far, no single study comprehensively discussed these drugs. This study reviews some anti-parasitic recommended drugs to treat COVID-19, in terms of function and  as well as clinical results. Finally, we briefly review the advanced techniques, such as artificial intelligence, that have been used to find effective drugs for the treatment of COVID-19.

摘要

新型冠状病毒肺炎是一种对全球人民构成严重威胁的突发公共卫生事件。鉴于该病毒传播速度极快,急需新型抗病毒药物。重新利用现有药物是首要策略。抗寄生虫药物是最早被考虑作为该疾病潜在治疗选择的药物之一。尽管许多论文分别讨论了各种抗寄生虫药物治疗新型冠状病毒肺炎的疗效,但迄今为止,尚无单一研究全面讨论这些药物。本研究从功能和临床结果方面综述了一些推荐用于治疗新型冠状病毒肺炎的抗寄生虫药物。最后,我们简要回顾了用于寻找治疗新型冠状病毒肺炎有效药物的先进技术,如人工智能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6095/8940209/8ab35b95377f/figure1.jpg

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