基于睾酮水平的电针治疗早泄的疗效研究。
Study on the Efficacy of Electric Acupuncture in the Treatment of Premature Ejaculation Based on Testosterone Level.
机构信息
The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang, China.
Heilongjiang Traditional Chinese Medicine Hospital, Heilongjiang, China.
出版信息
J Healthc Eng. 2022 Mar 22;2022:8331688. doi: 10.1155/2022/8331688. eCollection 2022.
OBJECTIVE
To investigate the clinical efficacy and possible mechanism of electroacupuncture in the treatment of premature ejaculation.
METHODS
50 cases of premature ejaculation patients who met the diagnostic criteria were randomly divided into 2 groups with 25 cases in each group. The observation group was treated with electroacupuncture, and the control group was treated with Longdan Xiegan decoction. The treatment period was 4 weeks. Ejaculation latency (IELT), sexual satisfaction score of patients, sexual satisfaction score of partners, testosterone test, and drug safety assessment were performed in all 4 groups before and after treatment.
RESULTS
IELT was prolonged in all groups after treatment, the difference was statistically significant ( < 0.05). At the same time, the IELT of the observation group was significantly higher than that of the control group after treatment. Life satisfaction scores of patients and spouses in 2 groups were improved after treatment compared with before treatment, the difference was statistically significant ( < 0.05). After treatment, the satisfaction scores of patients and spouses in the observation group were higher than those in the control group, and the difference was statistically significant ( < 0.05). Before treatment, there was no significant difference in serum testosterone levels among all groups ( > 0.05). Serum testosterone levels in all groups were decreased after treatment compared with before treatment, with statistical significance ( < 0.05). After treatment, the serum testosterone level of the observation group was lower than that of the control group, and the difference was statistically significant ( < 0.05). During the treatment, the adverse reactions in each group disappeared after treatment, and no obvious abnormality was observed in the safety indicators.
CONCLUSION
Electroacupuncture can improve the symptoms of premature ejaculation, which may be related to the regulation of serum testosterone by acupuncture.
目的
探讨电针对早泄的临床疗效及可能机制。
方法
将符合诊断标准的 50 例早泄患者随机分为 2 组，每组 25 例。观察组采用电针治疗，对照组采用龙胆泻肝汤治疗。治疗周期为 4 周。所有患者在治疗前后均进行射精潜伏期（IELT）、患者性满意度评分、性伴侣性满意度评分、睾酮检测及药物安全性评估。
结果
所有患者治疗后 IELT 均延长，差异有统计学意义（ < 0.05）。同时，观察组治疗后的 IELT 明显高于对照组。2 组患者及配偶的生活满意度评分均较治疗前提高，差异有统计学意义（ < 0.05）。治疗后，观察组患者及配偶的满意度评分均高于对照组，差异有统计学意义（ < 0.05）。治疗前，各组血清睾酮水平差异无统计学意义（ > 0.05）。与治疗前相比，所有患者治疗后血清睾酮水平均降低，差异有统计学意义（ < 0.05）。治疗后，观察组血清睾酮水平低于对照组，差异有统计学意义（ < 0.05）。治疗过程中，各患者不良反应均在治疗后消失，安全性指标未见明显异常。
结论
电针治疗可以改善早泄症状，这可能与针刺调节血清睾酮有关。
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