Dutta Siddhartha, Kaur Rimple J, Bhardwaj Pankaj, Ambwani Sneha, Godman Brian, Jha Pallavi A, Sukhija Sanchi, Venkatesh Suman S, Lugova Halyna, Islam Salequl, Charan Jaykaran, Haque Mainul
Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Community and Family Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
J Family Med Prim Care. 2022 Feb;11(2):503-511. doi: 10.4103/jfmpc.jfmpc_1250_21. Epub 2022 Feb 16.
COVID-19 pandemic led to increased self-medication of antimicrobials, vitamins, and immune boosters among the common people and consuming without prescription can lead to adverse consequences including antimicrobial resistance.
A cross-sectional study was conducted on community pharmacies in Jodhpur, India. They were inquired regarding the prescription and increased sales (<25%, 25-50%, 50--75%, or 75--100%) of various medicines (Hydroxychloroquine, Azithromycin, Ivermectin, and Vitamin C) during the COVID-19 pandemic. Logistic regression analysis was conducted to assess the relationship between requests for certain COVID-19 medications and an increase in their sale.
A total of 204 pharmacies took part, and 88.23% reported patients to approach them without prescriptions. Most of the pharmacies revealed that <25% of patients came without prescription. The majority came for azithromycin (68%) and vitamin C (92%). Increased sales of the four targeted medications were seen by 85.92% of pharmacies compared to last year. A majority (51.5%) reported <25% increased sales of azithromycin, but no change in the sale of hydroxychloroquine and ivermectin. However, 39.6% reported >75% increase in vitamin C sales.
There was an increase in the demand for COVID-19 medications without prescription. This study was unable to detect a significant increase in sales of antimicrobials, which is encouraging.
新冠疫情导致普通民众自行服用抗菌药物、维生素和免疫增强剂的情况增多,无处方用药可能会导致包括抗菌药物耐药性在内的不良后果。
在印度焦特布尔的社区药店开展了一项横断面研究。询问这些药店在新冠疫情期间各种药物(羟氯喹、阿奇霉素、伊维菌素和维生素C)的处方情况以及销量增长情况(<25%、25 - 50%、50 - 75%或75 - 100%)。进行逻辑回归分析以评估对某些新冠药物的需求与销量增长之间的关系。
共有204家药店参与,88.23%的药店报告有患者无处方前来购药。大多数药店表示,<25%的患者无处方购药。大多数患者购买阿奇霉素(68%)和维生素C(92%)。与去年相比,85.92%的药店报告这四种目标药物的销量有所增加。大多数(51.5%)药店报告阿奇霉素销量增长<25%,但羟氯喹和伊维菌素的销量没有变化。然而,39.6%的药店报告维生素C销量增长>75%。
无处方购买新冠药物的需求有所增加。本研究未能检测到抗菌药物销量的显著增加,这令人鼓舞。