急性黄斑神经视网膜病变为 SARS-CoV-2 感染的第一阶段。
Acute macular neuroretinopathy as the first stage of SARS-CoV-2 infection.
机构信息
Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
Department of Ophthalmology, IRCCS Ospedale San Raffaele, Vita-Salute University, Milan, Italy.
出版信息
Eur J Ophthalmol. 2023 May;33(3):NP105-NP111. doi: 10.1177/11206721221090697. Epub 2022 Mar 31.
INTRODUCTION
To report two cases of Acute Macular Neuroretinopathy (AMN) presented as the first stage of SARS-CoV-2 infection in two European countries during the third wave of pandemic viral infection in the early months of 2021.
OBSERVATIONS
A unilateral case of type 1 AMN in a man and a bilateral case of type 2 AMN in an otherwise heathy patients were reported. Sudden onset of paracentral scotoma characterized the cases with no systemic symptoms. Structural optical coherence tomography (OCT) shows multifocal middle and inner retinal hyperreflective infarctions. OCT-Angiography showed the presence of hypoperfusion of the deep capillary plexus (DCP) corresponding to the hyperreflective lesions visible on structural OCT, confirming the diagnosis.
CONCLUSIONS AND IMPORTANCE
Type 1 and type 2 AMN may be the first stage of SARS-CoV-2 infection. We suggest testing all patients with AMN for SARS-CoV-2. In our cases, the natural history of AMN associated with SARS-CoV-2 infection was similar to already described cases of AMN.
简介
报告两例急性黄斑神经视网膜病变（AMN），这两例均发生于 2021 年初第三波大流行病毒感染期间的两个欧洲国家，且均为 SARS-CoV-2 感染的首发阶段。
观察结果
报告了两例 AMN，一例为男性的 1 型 AMN，另一例为无其他健康问题的女性的 2 型 AMN。病例均以单侧中央旁暗点为特征，无全身症状。结构光相干断层扫描（OCT）显示多发性中内层视网膜高反射性梗死。OCT 血管造影显示深层毛细血管丛（DCP）灌注不足，与结构 OCT 上可见的高反射病变相对应，从而确诊。
结论和重要性
1 型和 2 型 AMN 可能为 SARS-CoV-2 感染的首发阶段。我们建议对所有 AMN 患者进行 SARS-CoV-2 检测。在我们的病例中，与 SARS-CoV-2 感染相关的 AMN 的自然病程与已描述的 AMN 病例相似。
Zotero 插件