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双侧急性黄斑神经视网膜病变(AMN)与 COVID-19 及其临床经过。

Bilateral Acute Macular Neuroretinopathy (AMN) after COVID-19 and its Clinical Course.

机构信息

Augenklinik, Universitätsklinikum Erlangen, Deutschland.

出版信息

Klin Monbl Augenheilkd. 2024 Jan;241(1):95-101. doi: 10.1055/a-2022-8462. Epub 2023 May 8.

Abstract

Acute macular neuroretinopathy (AMN) is a rare disease entity. It is mainly observed in young women with a history of influenza-like infection or who have been taking oral contraceptives for several years. Patients typically describe subjective visual deterioration and mono- or bilateral paracentral relative scotomas. In some cases, funduscopic ophthalmic examination may reveal subtle sharply demarcated flat lesions of reddish-brown or orange colour in the macular region. Diagnosis is usually made by near-infrared fundus imaging which shows hyporeflective areas, and SD-OCT imaging which manifests changes in the outer retinal layers. In the following, three patient cases with bilateral AMN are described which occurred in direct temporal relationship to a recent SARS-CoV-2 infection.

摘要

急性黄斑神经视网膜病变(AMN)是一种罕见的疾病。它主要发生在有流感样感染史或长期服用口服避孕药的年轻女性中。患者通常描述主观视力下降和单眼或双眼旁中心相对暗点。在某些情况下,眼底眼科检查可能会发现黄斑区域出现细微的边界清晰的棕红色或橙红色平坦病变。诊断通常通过近红外眼底成像来进行,该成像显示低反射区域,而 SD-OCT 成像则显示外视网膜层的变化。在下面,描述了三例与最近的 SARS-CoV-2 感染直接相关的双侧 AMN 患者病例。

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