Ewy G A
Circulation. 1986 Dec;74(6 Pt 2):IV98-101.
The finding that blood flow during external chest compression may be due to increased intrathoracic pressure, and the subsequent reporting of increased carotid blood flow with simultaneous ventilation and chest compression or with abdominal binding during CPR ignited a flurry of investigations into alternative approaches to CPR. A number of alterations of the conventional CPR technique were proposed, many resulting in improved hemodynamics when compared with standard CPR techniques in the same subject. However, some of the proposed methods increased cerebral blood flow but decreased myocardial perfusion. Others improved systolic pressures but decreased vital organ blood flow. More importantly, most studies with survival as an end point failed to show a benefit when alternative approaches to CPR were used. Therefore, it is unlikely that there will be significant changes in the recommendations for the use of adjuncts during CPR. Not all studies support the conclusion that blood flow during closed-chest compression is secondary to increased intrathoracic pressure. It is probable that in man there is a spectrum. In some individuals the predominant mechanism of blood flow during CPR may be cardiac and/or vascular compression, and in others flow may be secondary to an increased intrathoracic pressure.
体外胸外按压期间的血流可能归因于胸腔内压力升高,这一发现以及随后关于在心肺复苏期间同步通气和胸外按压或腹部捆绑时颈动脉血流增加的报告,引发了对心肺复苏替代方法的一系列研究。人们提出了许多对传统心肺复苏技术的改变,与同一受试者的标准心肺复苏技术相比,许多改变都能改善血流动力学。然而,一些提出的方法增加了脑血流量,但减少了心肌灌注。其他方法提高了收缩压,但减少了重要器官的血流量。更重要的是,大多数以生存为终点的研究在使用心肺复苏替代方法时未能显示出益处。因此,心肺复苏期间辅助手段使用建议不太可能有重大改变。并非所有研究都支持闭胸按压期间的血流是胸腔内压力升高所致这一结论。在人类中可能存在多种情况。在一些个体中,心肺复苏期间血流的主要机制可能是心脏和/或血管受压,而在另一些个体中,血流可能继发于胸腔内压力升高。