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First-time imaging of [Zr]trastuzumab in breast cancer using a long axial field-of-view PET/CT scanner.

作者信息

Brouwers Adrienne H, van Sluis Joyce, van Snick Johannes H, Schröder Carolina P, Baas Inge O, Boellaard Ronald, Glaudemans Andor W J M, Borra Ronald J H, Lammertsma Adriaan A, Dierckx Rudi A J O, Tsoumpas Charalampos

机构信息

University of Groningen, University Medical Center Groningen, Medical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, PO Box 30001, 9700 RB, Groningen, The Netherlands.

Netherlands Cancer Institute, Department of Medical Oncology, Amsterdam, The Netherlands.

出版信息

Eur J Nucl Med Mol Imaging. 2022 Aug;49(10):3593-3595. doi: 10.1007/s00259-022-05777-x. Epub 2022 Apr 1.

Abstract
摘要

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Feasibility of PET/CT system performance harmonisation for quantitative multicentre Zr studies.
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Zr-trastuzumab PET supports clinical decision making in breast cancer patients, when HER2 status cannot be determined by standard work up.
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Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer.
Clin Pharmacol Ther. 2010 May;87(5):586-92. doi: 10.1038/clpt.2010.12. Epub 2010 Mar 31.

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