Reno School of Medicine, University of Nevada, Reno, Nevada, USA.
Department of Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Laryngoscope. 2023 Jan;133(1):116-123. doi: 10.1002/lary.30130. Epub 2022 Apr 2.
To measure baseline human papillomavirus (HPV) vaccination rates among tertiary and community-based Otolaryngology - Head and Neck Surgery (Oto-HNS) clinic patients and to determine risk factors for under-vaccination.
Retrospective chart review of patients aged 9 to 26 years presenting to an Oto-HNS clinic from 2017 to 2019. Patients were considered complete for HPV vaccination if they received two doses of HPV vaccine with the first dose received before age 15 years or three doses of HPV vaccine otherwise.
8,532 unique patients met the criteria. At the index visit, 3,110 (36.5%) had completed the HPV series, 5,422 (63.5%) were due for one or more doses, with 4,981 (58.4%) eligible for vaccination at the time of their appointment. Of those dues, most (3,148/5,422 or 58%) were past due by age (≥13 years old). Of the 3,148 patients past due, 745 (23.7%) were partially vaccinated and 2,403 (76.3%) were vaccine naïve. Male sex and younger age were both independently associated with incomplete vaccination (p < 0.0001).
This study demonstrates that the implementation of on-site HPV vaccination has the potential to increase the opportunities for vaccination among vaccine-eligible patients, especially among young males. Otolaryngologists have the potential to provide meaningful preventive services in the fight against HPV-mediated disease.
3 Laryngoscope, 133:116-123, 2023.
测量三级和社区耳鼻喉科-头颈外科（Oto-HNS）诊所患者的人乳头瘤病毒（HPV）疫苗接种基线率，并确定疫苗接种不足的危险因素。
回顾性分析 2017 年至 2019 年在耳鼻喉科诊所就诊的 9 至 26 岁患者的病历。如果患者接受了两剂 HPV 疫苗接种，且第一剂在 15 岁之前接种，或接受了三剂 HPV 疫苗接种，则认为其 HPV 疫苗接种完成。
共有 8532 名患者符合标准。在就诊时，3110 名（36.5%）患者已完成 HPV 系列接种，5422 名（63.5%）需要接种一剂或多剂疫苗，其中 4981 名（58.4%）在预约时符合接种条件。在这些需要接种的患者中，大多数（3148/5422 或 58%）已超过接种年龄（≥13 岁）。在 3148 名逾期未接种的患者中，745 名（23.7%）部分接种，2403 名（76.3%）未接种疫苗。男性和年龄较小均与接种不完全独立相关（p<0.0001）。
本研究表明，现场 HPV 疫苗接种的实施有可能增加疫苗接种机会，特别是在年轻男性中。耳鼻喉科医生有潜力在抗击 HPV 介导疾病的斗争中提供有意义的预防服务。
3 Laryngoscope, 133:116-123, 2023.
