Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269,
Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269.
Avian Dis. 2022 Mar;66(1):1-4. doi: 10.1637/aviandiseases-D-22-00003. Epub 2022 Mar 30.
Necrotic enteritis (NE) is a serious disease of chickens and turkeys that causes significant economic losses to the poultry industry. On the basis of studies in chickens, type G is considered by many to be the cause of NE in poultry. However, studies on isolates from Finnish and Italian turkeys with NE revealed that the vast majority were type A, and very few were type G. We therefore examined 74 isolates from U.S. turkeys with NE; 98% were type A and only 1% was type G. This result confirms that different types are involved in NE in turkeys when compared with chickens. We also examined the turkey isolates for other toxin genes associated with enteritis in various animal species, namely , , , , , and . The gene, which has been associated with enhanced virulence of in chickens, was only found in 1% of turkey NE isolates. The gene, which encodes enterotoxin (a major cause of food poisoning and non-foodborne -mediated diarrhea in humans) was also found in only 1% of our turkey NE isolates. Although which encodes for the beta2 toxin, was found in 73% of our NE isolates, it has also been found in similar percentages of isolates from turkeys with normal intestine. The , and genes were not detected among our isolates from turkeys.
坏死性肠炎（NE）是一种严重影响鸡和火鸡的疾病，给家禽业造成了巨大的经济损失。基于对鸡的研究，许多人认为 G 型是引起家禽 NE 的原因。然而，对来自芬兰和意大利具有 NE 的火鸡分离株的研究表明，绝大多数为 A 型，而 G 型非常少。因此，我们检查了 74 株来自美国具有 NE 的火鸡分离株；98%为 A 型，只有 1%为 G 型。这一结果证实了与鸡相比，不同的类型参与了火鸡的 NE。我们还检查了与各种动物肠炎相关的其他毒素基因，即 、 、 、 、 和 。与鸡中 增强毒力相关的 基因仅在 1%的火鸡 NE 分离株中发现。编码肠毒素（人类食物中毒和非食源性介导腹泻的主要原因）的 基因也仅在 1%的我们的火鸡 NE 分离株中发现。虽然编码β2 毒素的 基因在我们 73%的 NE 分离株中发现，但它也在具有正常肠道的火鸡分离株中以相似的百分比发现。我们从火鸡中分离的 、 和 基因未被检测到。
