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异位胰腺继发胃出口梗阻被误诊为胃癌:“病例报告”

Gastric outlet obstruction secondary to heterotopic pancreas being mistaken for gastric cancer: "Case report".

作者信息

Bejiga Gosa

机构信息

Adama Hospital Medical College, Adama, P.O. Box:84, Ethiopia.

出版信息

Int J Surg Case Rep. 2022 Apr;93:106974. doi: 10.1016/j.ijscr.2022.106974. Epub 2022 Mar 29.

DOI:10.1016/j.ijscr.2022.106974
PMID:35367947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8980623/
Abstract

INTRODUCTION

Heterotopic pancreas (HP) is an uncommon and often incidental finding in clinical practice. It is the presence of pancreatic tissue distinct from the normal pancreas and with its own ductal and vascular supply. Distal stomach is the most common location of heterotopic pancreas followed by duodenum and jejunum. Most patients with heterotopic pancreas are asymptomatic. Gastric outlet obstruction is a rare presentation of heterotopic pancreas that can follow chronic inflammation and fibrosis of the pylorus from pancreatic secretion, pancreatitis, or malignant transformation. Heterotopic pancreas can be confused for gastric carcinomas on CECT and endoscopy. The aim of this paper is to present a rare case of gastric outlet obstruction due to heterotopic pancreas, mistaken for gastric cancer on endoscopy and CT scan, and its management.

PRESENTATION OF THE CASE

A 45 years old male from Adama, Ethiopia presented with vomiting of 8 months, which worsened since the last one month. He has no history of smoking and diabetes. He occasionally drinks alcohol. Physical examination was normal. CECT scan and endoscopy suggested distal gastric cancer. Radical subtotal gastrectomy done as gastric cancer couldn't be ruled out with excellent outcome. Histopathology revealed obstructing prepyloric chronic fibrosis and heterotopic pancreas.

DISCUSSION

Heterotopic pancreas is a rare pathological entity, clinical diagnosis is difficult preoperatively and frequently an incidental finding at laparotomy.

CONCLUSION

Though rare, heterotopic pancreas can present with gastric outlet obstruction and cause diagnostic confusion with gastric cancer. Definitive diagnosis is by histology that can also guide limited resection intraoperatively.

摘要

引言

异位胰腺(HP)在临床实践中并不常见,且常为偶然发现。它是指存在与正常胰腺不同的胰腺组织,并有其自身的导管和血管供应。胃远端是异位胰腺最常见的部位,其次是十二指肠和空肠。大多数异位胰腺患者无症状。胃出口梗阻是异位胰腺的一种罕见表现,可继发于胰腺分泌、胰腺炎或恶性转化导致的幽门慢性炎症和纤维化。在CT增强扫描(CECT)和内镜检查中,异位胰腺可能会被误诊为胃癌。本文旨在介绍一例因异位胰腺导致胃出口梗阻的罕见病例,该病例在内镜检查和CT扫描中被误诊为胃癌及其治疗情况。

病例介绍

一名来自埃塞俄比亚阿达马的45岁男性,出现呕吐8个月,近1个月加重。他无吸烟和糖尿病史。偶尔饮酒。体格检查正常。CECT扫描和内镜检查提示胃远端癌。由于不能排除胃癌,遂行根治性次全胃切除术,术后效果良好。组织病理学检查显示幽门前慢性纤维化并伴有异位胰腺。

讨论

异位胰腺是一种罕见的病理实体,术前临床诊断困难,常在剖腹手术时偶然发现。

结论

尽管罕见,但异位胰腺可表现为胃出口梗阻,并与胃癌造成诊断上的混淆。最终诊断依靠组织学检查,这也可在术中指导有限切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/ec941d7df9fb/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/dc5ba3b3ca80/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/57ba1b339da8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/81dc23014a8e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/f9562aa85664/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/ec941d7df9fb/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/dc5ba3b3ca80/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/57ba1b339da8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/81dc23014a8e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/f9562aa85664/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954b/8980623/ec941d7df9fb/gr5.jpg

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