Goel Ruchi, Khanam Samreen, Shah Shalin, Saran Ravindra Kumar
Ophthalmology, Maulana Azad Medical College, New Delhi, India.
Pathology, Govind Ballabh Pant Hospital, New Delhi, India.
Case Rep Ophthalmol Med. 2022 Mar 25;2022:3032246. doi: 10.1155/2022/3032246. eCollection 2022.
A middle-aged lady presented with a firm, nontender mass on the left upper lid and area behind the left ear following lid reconstruction with postauricular graft for cicatricial ectropion 11 months prior. She had a similar mass on the right shin. She was diagnosed as a case of multiple keloids. Intralesional injection of triamcinolone acetonide suspension and 5-Fluorouracil (5-FU) in the upper lid keloid resulted in ulceration of its surface. Surgical excision, injection of 5-FU in the keloid bed with temporal forehead flap reconstruction, was performed. Occurrence of inadvertent postoperative wound infection with was treated with local dressing with colistimethate sodium. Adjuvant therapy with topical imiquimod cream 5% was given subsequently for 24 weeks with no recurrence of the lid keloid after 16 months. The patient was managed using a combination of conservative and surgical therapy and multidisciplinary team work and kept on a long term follow-up.
一位中年女性，11个月前因瘢痕性睑外翻行耳后皮瓣眼睑重建术，术后左上睑及左耳后区域出现一个质地硬、无压痛的肿块。她右小腿也有类似肿块。她被诊断为多发性瘢痕疙瘩。对上睑瘢痕疙瘩进行曲安奈德混悬液和5-氟尿嘧啶（5-FU）皮损内注射后，其表面发生溃疡。遂行手术切除，在瘢痕疙瘩创床注射5-FU并行颞部前额皮瓣重建。术后意外发生伤口感染，采用硫酸多粘菌素B局部换药治疗。随后给予5%咪喹莫特乳膏辅助治疗24周，16个月后睑部瘢痕疙瘩未复发。该患者采用保守治疗与手术治疗相结合以及多学科团队协作的方式进行管理，并进行长期随访。
