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准确的病灶定位有助于肾素瘤患者的保留肾单位手术:病例报告与讨论

Accurate lesion localisation facilitates nephron sparing surgery in reninoma patients: case report and discussion.

作者信息

Mondschein Romy, Kwan Edward, Abou-Seif Claire, Rajarubendra Nieroshan

机构信息

Monash Health Department of Urology, 62-70 Kangan Drive, Berwick, VIC, 3806, Australia.

Monash Health Department of Pathology, 246 Clayton Road, Clayton, VIC, 3800, Australia.

出版信息

Urol Case Rep. 2022 Mar 25;43:102069. doi: 10.1016/j.eucr.2022.102069. eCollection 2022 Jul.

Abstract

A 21-year-old female was referred with a suspected juxtaglomerular cell tumour (reninoma) in the superior pole of the left kidney. She underwent renal biopsy and renal vein sampling (RVS) to confirm the diagnosis. Following an uncomplicated laparoscopic partial nephrectomy, antihypertensive medications were ceased. Histopathology confirmed the diagnosis. Reninoma is a rare but reversible cause of secondary hypertension and should be considered along with primary hyperaldosteronism and pheochromocytoma when investigating hypertension in a young person. The subtle appearance of reninoma on imaging can necessitate other investigations to confirm the diagnosis. Definitive localisation is essential to prevent unnecessary loss of nephrons.

摘要

一名21岁女性因左肾上极疑似近球细胞肿瘤(肾瘤)前来就诊。她接受了肾活检和肾静脉采样(RVS)以确诊。在经历了一次无并发症的腹腔镜部分肾切除术后,停用了抗高血压药物。组织病理学确诊了该诊断。肾瘤是继发性高血压的一种罕见但可逆转的病因,在对年轻人进行高血压调查时,应与原发性醛固酮增多症和嗜铬细胞瘤一同考虑。肾瘤在影像学上的细微表现可能需要其他检查来确诊。明确的定位对于防止不必要的肾单位丢失至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4584/8965904/28037ba9f823/gr1.jpg

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