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Association of Polygenic Risk Score With Blood Pressure and Adverse Cardiovascular Outcomes in Individuals With Type II Diabetes: Insights From the ACCORD Trial.2型糖尿病患者多基因风险评分与血压及不良心血管结局的关联：来自ACCORD试验的见解
Hypertension. 2022 May;79(5):e100-e102. doi: 10.1161/HYPERTENSIONAHA.122.18976. Epub 2022 Apr 4.
2
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J Hypertens. 2006 Jan;24(1):208-10. doi: 10.1097/01.hjh.0000198038.01387.9b.
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[Renin-angiotensin system blockade reduces cardiovascular mortality and morbidity attributable to arterial hypertension by primary and secondary prevention. The end of the road?].[肾素-血管紧张素系统阻断通过一级和二级预防降低动脉高血压所致的心血管死亡率和发病率。这条路走到尽头了吗？]
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Combating hypertension beyond genome-wide association studies: Microbiome and artificial intelligence as opportunities for precision medicine.超越全基因组关联研究对抗高血压：微生物组与人工智能作为精准医学的机遇
Camb Prism Precis Med. 2023 May 16;1:e26. doi: 10.1017/pcm.2023.13. eCollection 2023.
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Association of a Multiancestry Genome-Wide Blood Pressure Polygenic Risk Score With Adverse Cardiovascular Events.多血统全基因组血压多基因风险评分与不良心血管事件的关联。
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本文引用的文献

1
10. Cardiovascular Disease and Risk Management: .10. 心血管疾病与风险管理： 。
Diabetes Care. 2021 Jan;44(Suppl 1):S125-S150. doi: 10.2337/dc21-S010.
2
Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial.2 型糖尿病冠状动脉风险评估的遗传工具：来自 ACCORD 临床试验的队列研究。
Diabetes Care. 2018 Nov;41(11):2404-2413. doi: 10.2337/dc18-0709. Epub 2018 Sep 27.
3
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.对超过 100 万人的基因分析确定了 535 个与血压特征相关的新基因座。
Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x. Epub 2018 Sep 17.
4
Effects of intensive glucose lowering in type 2 diabetes.强化降糖对2型糖尿病的影响。
N Engl J Med. 2008 Jun 12;358(24):2545-59. doi: 10.1056/NEJMoa0802743. Epub 2008 Jun 6.
5
Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure.在数量性状研究中对治疗效果进行校正：抗高血压治疗与收缩压
Stat Med. 2005 Oct 15;24(19):2911-35. doi: 10.1002/sim.2165.

Association of Polygenic Risk Score With Blood Pressure and Adverse Cardiovascular Outcomes in Individuals With Type II Diabetes: Insights From the ACCORD Trial.

作者信息

Parcha Vibhu, Pampana Akhil, Bress Adam P, Irvin Marguerite R, Arora Garima, Arora Pankaj

机构信息

Division of Cardiovascular Disease (V.P., A.P., G.A., P.A.).

Department of Population Health Sciences, University of Utah School of Medicine, Salt Lake City (A.B.).

出版信息

Hypertension. 2022 May;79(5):e100-e102. doi: 10.1161/HYPERTENSIONAHA.122.18976. Epub 2022 Apr 4.

DOI:10.1161/HYPERTENSIONAHA.122.18976
PMID:35369713
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9010352/
Abstract
摘要