急性肾损伤的不常见病因。
Uncommon Causes of Acute Kidney Injury.
机构信息
Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Faculty Pavilion, 4th Floor, Pittsburgh, PA 15224, USA; Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, A919 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
出版信息
Crit Care Clin. 2022 Apr;38(2):317-347. doi: 10.1016/j.ccc.2021.11.010.
Acute kidney injury (AKI) is one of the most important complications of critical illness and a significant public health concern. AKI is commonly associated with sepsis, cardiac dysfunction, and exposure to nephrotoxic medication; however, less common causes of AKI can lead to devastating patient outcomes when the underlying diagnosis is missed or delayed. These uncommon causes of AKI fall into 3 large categories: structural, immune mediated, and microvascular, including various types of thrombotic microangiopathy. Kidney imaging, urine studies, and serum hemolytic studies should be a routine part of the evaluation of AKI among critically ill patients.
急性肾损伤 (AKI) 是危重病患者最重要的并发症之一，也是一个重大的公共卫生问题。AKI 通常与脓毒症、心功能障碍和接触肾毒性药物有关；然而，当潜在诊断被忽视或延迟时，AKI 的一些不太常见的原因会导致灾难性的患者结局。这些 AKI 的不常见原因可分为 3 大类：结构性、免疫介导性和微血管性，包括各种类型的血栓性微血管病。对于危重病患者的 AKI 评估，肾脏影像学、尿液研究和血清溶血研究应作为常规检查的一部分。
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