Jain Ashish, Yagnik K, Hussain Khandakar M, Naik Sarvesh, Sharma Tanvi, Shahab Asna, Khilan Muhammad Haroon
Internal Medicine, Conemaugh Memorial Medical Center, Johnstown, USA.
Medicine and Surgery, Government Medical College, Surat, IND.
Cureus. 2022 Feb 22;14(2):e22489. doi: 10.7759/cureus.22489. eCollection 2022 Feb.
Brugada syndrome (BrS) is an inherited arrhythmia syndrome in which asymptomatic patients tend to develop fatal arrhythmias leading to sudden cardiac death (SCD) in asymptomatic or undiagnosed cases. This review tries to shed light on pyrexia being one of the triggers to cause SCD secondary to fatal arrhythmias in patients of BrS. Pyrexia, electrolyte imbalance, alcohol intake, and drugs are common triggering factors for fatal arrhythmias in patients with BrS. Most patients are asymptomatic, while the most common form of presentation that brings the patient under medical attention is syncope or SCD. Hence, patients, especially young, who present with syncope or aborted episode of SCD with typical EKG patterns, should undergo further workup. It is essential to educate patients about the condition, possible triggers, and the importance of refraining them.
Brugada综合征（BrS）是一种遗传性心律失常综合征，在无症状患者中，无症状或未被诊断的病例往往会发生致命性心律失常，导致心源性猝死（SCD）。本综述试图阐明发热是导致BrS患者继发于致命性心律失常的心源性猝死的诱因之一。发热、电解质失衡、饮酒和药物是BrS患者发生致命性心律失常的常见触发因素。大多数患者无症状，而引起患者就医的最常见表现形式是晕厥或心源性猝死。因此，出现晕厥或伴有典型心电图模式的心源性猝死未遂发作的患者，尤其是年轻人，应接受进一步检查。对患者进行有关病情、可能的触发因素以及避免触发因素的重要性的教育至关重要。
