Cohen J, Debache C, Pez J P, Junca A M, Cohen-Bacrie P
J In Vitro Fert Embryo Transf. 1986 Oct;3(5):309-13. doi: 10.1007/BF01133391.
Two hundred twenty-two patients took part in a trial of follicle puncture via the transvaginal route under sonographic control for the purpose of in vitro fertilization (IVF). Induction protocols were mainly human menopausal gonadotropin (hMG) + human chorionic gonadotropin (hCG) and clomiphene + hMC + hCG. In 79.7% oocyte aspiration could be achieved without difficulty via the transvaginal route. An average number of 4.7 oocytes per attempt was obtained; 10.7% evolutive pregnancies were obtained. No major incident was noted. This technique offers several crucial advantages: it reduces surgical risk, reduces the length of the patient's stay in hospital as well as the overall cost of the procedure, and it also makes possible puncture in some cases hitherto regarded as excluded.
222名患者参与了一项在超声引导下经阴道途径进行卵泡穿刺以用于体外受精（IVF）的试验。诱导方案主要是人类绝经期促性腺激素（hMG）+人绒毛膜促性腺激素（hCG）以及克罗米芬+hMC+hCG。79.7%的患者经阴道途径可顺利完成卵母细胞抽吸。每次尝试平均获得4.7个卵母细胞；获得了10.7%的妊娠进展。未观察到重大事件。该技术具有几个关键优势：它降低了手术风险，缩短了患者的住院时间以及手术的总体费用，并且在一些以前被视为禁忌的情况下也使穿刺成为可能。
