Ryu Jihoon, Kang Gi-Jong, Kim Onnuri, Park Jae-Yeon, Shin Hyun-Jin
Research Institute of Veterinary Medicine, Daejeon, South Korea.
Laboratory of Infectious Disease, College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
Front Vet Sci. 2022 Mar 15;8:802816. doi: 10.3389/fvets.2021.802816. eCollection 2021.
Because the porcine epidemic diarrhea virus (PEDV) is a critical pathogen resulting in rapid spreading and high mortality rates in piglets, understanding of the transmission route of PEDV is required for its controlling. Until now, it is well known that PEDV transmission routes are various, such as fecal-oral route, contaminated feed, farmworkers, and transport vehicles. However, unlike several swine-infected viruses, there were no reports of vertical transmission with PEDV. In our study, we confirmed possible vertical transmission of PEDV. We confirmed PEDV in piglet testicles and umbilical cords from PEDV-positive sow. These findings are direct evidence that PEDV is transmitted vertically through placenta. This is the first report on transplacental transmission of PEDV and will be very important information for controlling PED.
由于猪流行性腹泻病毒（PEDV）是导致仔猪快速传播和高死亡率的关键病原体，因此控制PEDV需要了解其传播途径。到目前为止，众所周知，PEDV的传播途径多种多样，如粪口途径、受污染的饲料、农场工人和运输车辆。然而，与几种感染猪的病毒不同，尚无PEDV垂直传播的报道。在我们的研究中，我们证实了PEDV可能的垂直传播。我们在来自PEDV阳性母猪的仔猪睾丸和脐带中检测到了PEDV。这些发现是PEDV通过胎盘垂直传播的直接证据。这是关于PEDV经胎盘传播的首次报道，对于控制猪流行性腹泻将是非常重要的信息。
