Cramer B C, Jequier S, de Chadarevian J P
J Ultrasound Med. 1986 Nov;5(11):633-8. doi: 10.7863/jum.1986.5.11.633.
A prospective renal ultrasound study of 134 newborns (49 prematures weighing less than 2500 g and 85 more mature babies) was undertaken to investigate factors associated with increased renal cortical echogenicity (RCE). Increased RCE was seen in 39 (29 per cent) babies. It was significantly related to body weight, age, medical status, blood urea nitrogen, and serum creatinine. In view of the interdependence of these factors, however, multivariate analysis was performed, which revealed that age was the most important factor associated with increased echogenicity (r = -0.46), and the other factors had only small independent effects, increasing the multiple r to 0.56. The authors conclude that an infant's immaturity is the most important determinant of increased RCE.
对134名新生儿（49名体重不足2500克的早产儿和85名足月婴儿）进行了一项前瞻性肾脏超声研究，以调查与肾皮质回声增强（RCE）增加相关的因素。39名（29%）婴儿出现了RCE增加。它与体重、年龄、健康状况、血尿素氮和血清肌酐显著相关。然而，鉴于这些因素之间的相互依存关系，进行了多变量分析，结果显示年龄是与回声增强增加相关的最重要因素（r = -0.46），其他因素只有很小的独立影响，将多元相关系数提高到0.56。作者得出结论，婴儿的不成熟是RCE增加的最重要决定因素。
