Hricak H, Cruz C, Romanski R, Uniewski M H, Levin N W, Madrazo B L, Sandler M A, Eyler W R
Radiology. 1982 Jul;144(1):141-7. doi: 10.1148/radiology.144.1.7089245.
A retrospective study of 109 patients who underwent renal biopsy was designed to correlate the sonographic appearance of the kidney with the histologic changes and clinical and laboratory findings in various renal parenchymal diseases. The clinical, pathologic, and sonographic data were analyzed blindly and independently by a team from each corresponding discipline. There was no correlation between the specific sonographic appearance and the type of renal disease. There was a significant correlation between renal length and the prevalence of global sclerosis, focal tubular atrophy, and the number of hyaline casts per glomerulus. A significant positive correlation was also found between cortical echogenicity and the severity of global sclerosis, focal tubular atrophy, the number of hyaline casts per glomerulus, and focal leukocytic infiltration. While there was overall significant correlation between the degree of cortical echogenicity and blood urea nitrogen and creatinine concentrations in each group, a wide range of variance was present. It is not currently feasible to distinguish different types of renal medical disorders using diagnostic ultrasound.
一项针对109例接受肾活检患者的回顾性研究旨在将肾脏的超声表现与各种肾实质疾病的组织学变化、临床及实验室检查结果相关联。临床、病理及超声数据由各相应学科的团队进行盲法独立分析。特定的超声表现与肾脏疾病类型之间无相关性。肾长度与全球硬化、局灶性肾小管萎缩的患病率以及每个肾小球透明管型数量之间存在显著相关性。皮质回声与全球硬化、局灶性肾小管萎缩的严重程度、每个肾小球透明管型数量以及局灶性白细胞浸润之间也发现了显著正相关。虽然每组中皮质回声程度与血尿素氮和肌酐浓度之间总体存在显著相关性，但存在广泛的差异。目前使用诊断超声区分不同类型的肾脏疾病是不可行的。
