Özdal Pınar Çakar, Tugal-Tutkun Ilknur
Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.
Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
J Ophthalmic Inflamm Infect. 2022 Apr 4;12(1):14. doi: 10.1186/s12348-022-00292-4.
Systemic vasculitides are a large group of heterogeneous diseases characterized by inflammatory destruction of blood vessels targeting diverse organs and tissues including the eye. As the most vascularized layer of the eye, the choroid is expected to be affected in multiple systemic rheumatologic diseases with vascular involvement. While there are plenty of studies investigating retinal vascular involvement, choroidal vascular involvement in systemic vasculitides has not been investigated in isolation. However, choroidal manifestations including thickness changes, choroidal vasculitis and ischemia may be the earliest diagnostic features of systemic vasculitic diseases. Thus, multimodal imaging of the choroid may help early detection of choroidal involvement which may also have prognostic implications in these life-threatening diseases. This article aimed to review involvement of the choroid in systemic vasculitic diseases.
系统性血管炎是一大类异质性疾病，其特征是针对包括眼睛在内的各种器官和组织的血管发生炎症性破坏。作为眼睛血管最丰富的一层，脉络膜预计会在多种累及血管的系统性风湿性疾病中受到影响。虽然有大量研究调查视网膜血管受累情况，但系统性血管炎中脉络膜血管受累情况尚未单独进行研究。然而，包括厚度变化、脉络膜血管炎和缺血在内的脉络膜表现可能是系统性血管炎疾病的最早诊断特征。因此，脉络膜的多模态成像可能有助于早期发现脉络膜受累情况，这在这些危及生命的疾病中也可能具有预后意义。本文旨在综述系统性血管炎疾病中脉络膜的受累情况。
