血清维生素 D 水平与 2 型糖尿病患者勃起功能障碍：系统评价和荟萃分析。
Serum Vitamin D Level and Erectile Dysfunction in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.
机构信息
The Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China,
The Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
出版信息
Urol Int. 2022;106(10):1025-1032. doi: 10.1159/000523691. Epub 2022 Apr 4.
INTRODUCTION
A few studies involved the relationship between vitamin D and diabetes mellitus (DM) with erectile dysfunction (ED), and no meta-analysis was conducted to pool these data. The main purpose of our study was to examine the changes in serum vitamin D levels in patients with DM combined with ED.
METHODS
An extensive search was performed, including the following words: "erectile dysfunction," "diabetes," and "vitamin D." Databases, including Cochrane Library, PubMed, and Web of Science, were retrieved to identify studies published up to September 30, 2021. Four studies were eligible for our meta-analysis.
RESULTS
The weighted mean difference and their corresponding 95% confidence intervals were calculated to the data we selected. The results showed that the level of vitamin D in DM with ED was significantly lower (12.5 nmol/mL) than patients with diabetes alone (p = 0.002).
CONCLUSION
Our novel meta-analysis suggests that vitamin D may be a risk factor for DM with ED, which can provide a new idea for the treatment and prevention of DM with ED.
简介
有几项研究涉及维生素 D 与糖尿病（DM）和勃起功能障碍（ED）之间的关系，但没有进行荟萃分析来汇总这些数据。我们研究的主要目的是检查合并 ED 的 DM 患者血清维生素 D 水平的变化。
方法
进行了广泛的搜索，包括以下关键词：“勃起功能障碍”、“糖尿病”和“维生素 D”。检索了 Cochrane 图书馆、PubMed 和 Web of Science 等数据库，以确定截至 2021 年 9 月 30 日发表的研究。有四项研究符合我们的荟萃分析标准。
结果
我们对所选数据计算了加权均数差值及其相应的 95%置信区间。结果表明，合并 ED 的 DM 患者的维生素 D 水平明显较低（12.5nmol/mL）（p=0.002）。
结论
我们的新荟萃分析表明，维生素 D 可能是合并 ED 的 DM 的一个危险因素，这为 ED 合并 DM 的治疗和预防提供了新的思路。
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