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脊髓髓内病变:单中心经验

Intramedullary Spinal Cord Lesions: A Single-Center Experience.

作者信息

Jecko Vincent, Roblot Paul, Mongardi Lorenzo, Ollivier Morgan, Piccoli Natalia Delgado, Charleux Thomas, Wavasseur Thomas, Gimbert Edouard, Liguoro Dominique, Chotard Guillaume, Vignes Jean-Rodolphe

机构信息

Department of Neurosurgery, University Hospital of Bordeaux, Bordeaux, France.

University of Bordeaux, Bordeaux, France.

出版信息

Neurospine. 2022 Mar;19(1):108-117. doi: 10.14245/ns.2143190.595. Epub 2022 Mar 31.

Abstract

OBJECTIVE

Spinal cord tumors constitute a small part of spinal surgery owing to their rarity. This retrospective study describes their current management.

METHODS

Forty-eight patients were treated for an intramedullary tumor between 2014 and 2020 at a single institution. Patients' files were retrospectively studied. We detailed clinical status according to neurological deficit and ambulatory ability using the modified McCormick Scale, radiological features like number of levels, associated syringomyelia, surgical technique with or without intraoperative electrophysiological monitoring, pathological findings, and postoperative outcome.

RESULTS

The median age of this population was 43 years, including 5 patients under 18 years. The median delay before first neurosurgical contact was 3 months after the first clinical complaint. Treatment was gross total resection in 43.8%, subtotal resection in 50.0%, and biopsy in 6.2%. A laminectomy was performed for all the patients except 2 operated using the laminoplasty technique. Pathological findings were ependymoma in 43.8%, hemangioblastoma in 20.8%, and pilocytic astrocytoma in 10.4%. Six patients were reoperated for a tumor recurrence less than 2 years after the first surgical resection. One patient was reoperated for a postoperative cervical kyphosis.

CONCLUSION

Intramedullary tumors are still a challenging disease and they are treated by various surgical techniques. They must be managed in a specialized center including a trained surgical, radiological, electrophysiological, and pathological team. Arthrodesis must be discussed before performing extensive laminectomy to avoid postoperative kyphosis.

摘要

目的

脊髓肿瘤因其罕见性在脊柱外科手术中占比小。本回顾性研究描述了其当前的治疗情况。

方法

2014年至2020年期间,在一家机构对48例髓内肿瘤患者进行了治疗。对患者病历进行回顾性研究。我们根据神经功能缺损和行走能力,使用改良的麦考密克量表详细描述了临床状况,包括病变节段数量、相关脊髓空洞症等放射学特征,有无术中电生理监测的手术技术,病理结果以及术后结局。

结果

该人群的中位年龄为43岁,其中5例患者年龄在18岁以下。首次神经外科就诊前的中位延迟时间为首次出现临床症状后的3个月。治疗方式为全切除的占43.8%,次全切除的占50.0%,活检的占6.2%。除2例采用椎板成形术外,所有患者均进行了椎板切除术。病理结果显示室管膜瘤占43.8%,血管母细胞瘤占20.8%,毛细胞型星形细胞瘤占10.4%。6例患者在首次手术切除后不到2年因肿瘤复发再次手术。1例患者因术后颈椎后凸畸形再次手术。

结论

髓内肿瘤仍然是一种具有挑战性的疾病,采用多种手术技术进行治疗。必须在包括训练有素的外科、放射学、电生理和病理团队的专业中心进行管理。在进行广泛椎板切除术之前必须讨论关节固定术,以避免术后后凸畸形。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4066/8987546/ffa9f563f588/ns-2143190-595f1.jpg

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