Abebaw Moyehodie Yikeber, Wale Muluneh Mitiku
Department of Statistics, Debre Tabor University, Debre Tabor, Ethiopia.
Int J Gen Med. 2022 Mar 29;15:3483-3496. doi: 10.2147/IJGM.S355377. eCollection 2022.
Heart rate is a significant modifiable factor in lowering mortality in heart failure patients. The heart rate, often known as the pulse rate, is the number of times the heart beats in a given amount of time. Irregular pulse rate or heart block are all measured using heart rate data. A higher heart rate has been associated with worse clinical outcomes. The main purpose of this study was to identify factors associated with the longitudinal pulse rate of congestive heart failure patients.
Hospital-based retrospective studies were conducted among 249 congestive heart failure patients who were 18 years old or older and who were on treatment follow-up from first February 2016 to thirty-one December 2017 in Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia.
Data were explored using descriptive statistics, individual and mean profile plots, and analyzed using linear mixed models. Out of the total 249 patients, 139 (55.8%) were females. The majority 179 (71.9%) of the CHF patients were rural residents. 65 (26.1%) patients had Hypertension, 30 (12.5%) patients had Diabetes Mellitus, 58 (23.3%) patients had Pneumonia. Thus age, LVEF, follow-up time in a month had a negative significant effect whereas NYHA class, male gender, pneumonia had a positive significant effect on the average evaluation of pulse rate of patients. The time interaction effect of NYHA Class (Time* NYHA Class), and LVEF (Time*LVEF) had a significant effect on average pulse rate evolution.
The variables age, LVEF, and follow-up time were negatively associated whereas, male gender, NYHA class, and presence of pneumonia were positively associated with the progression change of pulse rate of patients rate of progression of pulse rate decreases over time. Furthermore, health professionals give more attention to patients who are NYHA class IV, had low LVEF, pneumonic patients to reduce pulse rate during the follow-up time.
心率是降低心力衰竭患者死亡率的一个重要可调节因素。心率，通常也被称为脉搏率，是指心脏在给定时间内跳动的次数。不规则脉搏率或心脏传导阻滞都可通过心率数据来测量。较高的心率与较差的临床结果相关。本研究的主要目的是确定与充血性心力衰竭患者纵向脉搏率相关的因素。
在埃塞俄比亚巴赫达尔的费莱格·希沃特转诊医院，对249名18岁及以上且在2016年2月1日至2017年12月31日接受治疗随访的充血性心力衰竭患者进行了基于医院的回顾性研究。
使用描述性统计、个体和均值分布图对数据进行探索，并使用线性混合模型进行分析。在总共249名患者中，139名（55.8%）为女性。大多数充血性心力衰竭患者179名（71.9%）是农村居民。65名（26.1%）患者患有高血压，30名（12.5%）患者患有糖尿病，58名（23.3%）患者患有肺炎。因此，年龄、左心室射血分数、随访月数对患者脉搏率的平均评估有负向显著影响，而纽约心脏病协会（NYHA）分级、男性性别、肺炎对患者脉搏率的平均评估有正向显著影响。NYHA分级（时间NYHA分级）和左心室射血分数（时间左心室射血分数）的时间交互作用对平均脉搏率变化有显著影响。
年龄、左心室射血分数和随访时间与患者脉搏率的进展变化呈负相关，而男性性别、NYHA分级和肺炎的存在与患者脉搏率的进展变化呈正相关。随着时间的推移，脉搏率的进展率会降低。此外，医疗专业人员应更加关注NYHA分级为IV级、左心室射血分数低的患者以及肺炎患者，以在随访期间降低他们的脉搏率。
