Department of Mathematics and Statistics, International Islamic University, Islamabad, Pakistan.
Multiphysical Engineering Sciences, Aeronautical and Mechanical Engineering Department, Salford University, Salford, UK.
Proc Inst Mech Eng H. 2022 Jun;236(6):848-859. doi: 10.1177/09544119221086479. Epub 2022 Apr 4.
The heat-conducting nature of blood is critical in the human circulatory system and features also in important thermal regulation and blood processing systems in biomedicine. Motivated by these applications, in the present investigation, the classical Graetz problem in heat transfer is extended to the case of a bio-rheological fluid model. The Quemada bio-rheological fluid model is selected since it has been shown to be accurate in mimicking physiological flows (blood) at different shear rates and hematocrits. The steady two-dimensional energy equation without viscous dissipation in stationary regime is tackled via a separation of variables approach for the isothermal wall temperature case. Following the introduction of transformation variables, the ensuing dimensionless boundary value problem is solved numerically via based algorithm known as (a finite difference code that implements the four-stage Lobatto IIIa collocation formula). Numerical validation is also presented against two analytical approaches namely, series solutions and Kummer function techniques. Axial conduction in terms of Péclet number is also considered. Typical values of Reynolds number and Prandtl number are used to categorize the vascular regions. The graphical representation of mean temperature, temperature gradient, and Nusselt numbers along with detail discussions are presented for the effects of Quemada non-Newtonian parameters and Péclet number. The current analysis may also have potential applications for the development of microfluidic and biofluidic devices particularly which are used in the diagnosis of diseases in addition to blood oxygenation technologies.
血液的导热性质在人体循环系统中至关重要,在生物医学中的重要热调节和血液处理系统中也有体现。受这些应用的启发,本研究将经典的热传递 Graetz 问题扩展到生物流变学流体模型的情况。选择 Quemada 生物流变学流体模型是因为它已被证明在不同剪切率和血细胞比容下准确模拟生理流动(血液)。对于等温壁温情况,通过变量分离方法解决稳态二维无粘性耗散能量方程。引入变换变量后,通过基于 的算法(实现四阶 Lobatto IIIa 配置公式的有限差分代码)数值求解无量纲边值问题。还针对两种分析方法(级数解和 Kummer 函数技术)进行了数值验证。还考虑了轴向热传导的 Peclet 数。使用典型的雷诺数和普朗特数来对血管区域进行分类。给出了平均温度、温度梯度和努塞尔数的图形表示以及详细讨论,以研究 Quemada 非牛顿参数和 Peclet 数的影响。目前的分析也可能对微流控和生物流体设备的发展具有潜在应用,特别是在疾病诊断以及血液氧合技术之外的应用。