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癌症患者的新冠病毒病结局及风险因素

Outcomes of COVID-19 and risk factors in patients with cancer.

作者信息

Sengar Manju, Chinnaswamy Girish, Ranganathan Priya, Ashok Apurva, Bhosale Shilpushp, Biswas Sanjay, Chaturvedi Pankaj, Dhamne Chetan, Divatia Jigeeshu, D'Sa Karishma, Jain Hasmukh, Laskar Sarbani, Moulik Nirmalya Roy, Mummudi Naveen, Nair Sindhu, Nayak Lingaraj, Nayak Prakash, Patkar Shraddha, Pawaskar Preeti, Ramaswamy Anant, Shetty Omshree, Singh Arjun, Sridhar Epari, Thorat Jayashree, Badwe Rajendra, Pramesh C S

机构信息

Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

出版信息

Nat Cancer. 2022 May;3(5):547-551. doi: 10.1038/s43018-022-00363-4. Epub 2022 Apr 4.

Abstract

Patients with cancer are at higher risk for adverse coronavirus disease 2019 (COVID-19) outcomes. Here, we studied 1,253 patients with cancer, who were diagnosed with severe acute respiratory syndrome coronavirus 2 at a tertiary referral cancer center in India. Most patients had mild disease; in our settings, recent cancer therapies did not impact COVID-19 outcomes. Advancing age, smoking history, concurrent comorbidities and palliative intent of treatment were independently associated with severe COVID-19 or death. Thus, our study provides useful insights into cancer management during the COVID-19 pandemic.

摘要

癌症患者出现新型冠状病毒肺炎(COVID-19)不良结局的风险更高。在此,我们研究了1253例癌症患者,这些患者在印度一家三级转诊癌症中心被诊断感染严重急性呼吸综合征冠状病毒2。大多数患者病情较轻;在我们的研究环境中,近期的癌症治疗并未影响COVID-19的结局。年龄增长、吸烟史、并发疾病以及治疗的姑息意图与严重COVID-19或死亡独立相关。因此,我们的研究为COVID-19大流行期间的癌症管理提供了有用的见解。

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