Department of Urology, Korle Bu Teaching Hospital, Accra, Ghana.
Department of Surgery, University of Health and Allied Sciences, Ho, Ghana.
Pan Afr Med J. 2022 Jan 13;41:33. doi: 10.11604/pamj.2022.41.33.29970. eCollection 2022.
Penile cancer is a rare malignancy worldwide except in parts of Africa, Asia and Latin America where higher incidences have been reported. The disease leads to serious physical disfigurement of the male genitalia which can have debilitating consequences, thus it may alter micturition patterns and impair penetrative sexual intercourse. The lack of cancer registries and epidemiological surveillance programs in Ghana makes estimation of the prevalence in Ghana difficult hence to advance the course of knowledge, awareness and prevention of penile cancers, it is imperative that such cases are brought to the fore and discussed. We report two cases of penile cancer that had partial penectomy and inguinal lymphadenectomy at the Korle Bu Teaching Hospital. Clinical findings and intervention of these reported cases highlight the management process and it further assessed the psychological impact of intervention. The two patients presented to our outpatient department with penile lesions which were confirmed to be penile cancer. The first patient presented with a 30 year history with recurrent ulceration while the other presented with just 1 (one) year history of penile lesion. Both patients required partial penectomy and inguinal lymphadenopathy in the treatment of their condition. The major risk factors as reported in this case study, include uncircumcision, previous treatment for sexually transmitted infections, multiple sexual partners and smoking. Treatment is associated with reduction in sexual function although quality of life may remain satisfactory. Strong family and psychological support are key cornerstones for good treatment outcomes.
阴茎癌在全球范围内较为罕见,除了在非洲、亚洲和拉丁美洲部分地区,这些地区的发病率较高。这种疾病会导致男性生殖器严重的身体畸形,从而产生严重后果,可能会改变排尿模式并影响性行为。加纳缺乏癌症登记处和流行病学监测计划,因此难以估计加纳的患病率。为了推进对阴茎癌的认知、意识和预防,必须将这些病例摆在突出位置并加以讨论。我们报告了在科雷布教学医院接受部分阴茎切除术和腹股沟淋巴结清扫术的两例阴茎癌病例。这些报告病例的临床发现和干预突出了治疗过程,并进一步评估了干预的心理影响。两名患者因阴茎病变就诊于我们的门诊部,经确诊为阴茎癌。第一例患者的病史为 30 年,反复出现溃疡,另一例患者的病史为 1 年,仅有阴茎病变。两名患者均需要接受部分阴茎切除术和腹股沟淋巴结清扫术治疗。该病例研究报告的主要危险因素包括包茎、以前治疗过性传播感染、多个性伴侣和吸烟。治疗会降低性功能,尽管生活质量可能仍令人满意。强有力的家庭和心理支持是取得良好治疗效果的关键基石。