Denton Christopher P, Campochiaro Corrado, Bruni Cosimo, Distler Oliver, Iagnocco Annamaria, Matucci Cerinic Marco
Division of Medicine, Department of Inflammation, Centre for Rheumatology and Connective Tissue Diseases, Royal Free Campus, University College London, London, UK.
Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.
J Scleroderma Relat Disord. 2021 Feb;6(1):58-65. doi: 10.1177/2397198320963393. Epub 2020 Oct 18.
COVID-19, caused by infection of the novel coronavirus SARS-CoV-2, has caused a pandemic of enormous impact that has challenged healthcare and political system throughout the world. This new health emergency has occurred on top of the usual burden of diseases, including systemic sclerosis, and has led to many unanticipated consequences. An early consequence of the pandemic was postponement of the Sixth Systemic Sclerosis World Congress that was recently completed as a successful virtual congress with more than 1000 delegates. In this article, we summarise the relevance and impact of COVID-19 from the perspective of systemic sclerosis. Shared concepts of pathogenesis are considered, and the relevant literature emerging about COVID-19 and systemic sclerosis summarised. The specific impact of this pandemic on delivery of optimal scleroderma care is considered, together with the broader effect on rheumatic and musculoskeletal diseases and the activities of European League Against Rheumatism. As the World continues to struggle against this new infectious disease, it is notable that expertise and growing understanding of systemic sclerosis has been able to help tackle COVID-19. Moreover, the essential adjustments to deliver clinical care and establishment of new ways of working due to the pandemic have offered potential avenues for future improvement in systemic sclerosis care.
新型冠状病毒SARS-CoV-2感染引发的COVID-19已造成一场具有巨大影响的大流行，对全球医疗保健和政治体系构成了挑战。这场新的卫生紧急情况叠加在包括系统性硬化症在内的常见疾病负担之上，引发了许多意想不到的后果。大流行的一个早期后果是第六届系统性硬化症世界大会推迟召开，该大会最近作为一次成功的虚拟会议圆满结束，有1000多名代表参加。在本文中，我们从系统性硬化症的角度总结了COVID-19的相关性和影响。我们考虑了发病机制的共同概念，并总结了有关COVID-19和系统性硬化症的相关文献。我们探讨了这场大流行对提供最佳硬皮病护理的具体影响，以及对风湿性和肌肉骨骼疾病以及欧洲抗风湿病联盟活动的更广泛影响。在世界继续与这种新型传染病作斗争之际，值得注意的是，对系统性硬化症的专业知识和日益深入的了解有助于应对COVID-19。此外，由于大流行而对提供临床护理进行的必要调整以及新工作方式的建立，为未来系统性硬化症护理的改进提供了潜在途径。
