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一个具有挑战性的 COVID-19 病例:一名 COVID-19 阳性青少年出现严重糖尿病酮症酸中毒、耐药性高血压。

A challenging case of COVID-19: a COVID-19 positive adolescent presented with severe diabetic ketoacidosis, resistant hypertension.

机构信息

Department of Pediatric Endocrinology and Metabolism, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Department of Pediatric Nephrology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

出版信息

BMC Endocr Disord. 2022 Apr 5;22(1):90. doi: 10.1186/s12902-022-00979-8.

DOI:10.1186/s12902-022-00979-8
PMID:35382801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8981183/
Abstract

BACKGROUND

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus which causes COVID-19. It binds to the angiotensin-converting enzyme 2 (ACE2) receptors, expressed in key metabolic organs and tissues, including pancreatic beta cells, adipose tissue, the small intestine, and kidneys. This condition has been linked to a variety of additional symptoms, including acute encephalopathy, changes in consciousness, and even gastrointestinal bleeding.

CASE PRESENTATION

In this study, we have reported a 13-year-old boy, 69 kg, with SARS-COV-2 infection. In this case, multiple systems, including the endocrine, renal, pulmonary, gastrointestinal, and nervous systems, were affected.

CONCLUSIONS

It is speculated that different manifestations of COVID-19 can be seen in clinical settings, and practitioners should be more cautious not to miss the chimeric characteristics of COVID-19 infection.

摘要

背景

严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是一种导致 COVID-19 的病毒。它与血管紧张素转换酶 2(ACE2)受体结合,这些受体在包括胰腺β细胞、脂肪组织、小肠和肾脏在内的关键代谢器官和组织中表达。这种情况与多种其他症状有关,包括急性脑病、意识改变,甚至胃肠道出血。

病例介绍

在这项研究中,我们报告了一例 13 岁男孩,69kg,患有 SARS-CoV-2 感染。在这种情况下,包括内分泌、肾脏、肺部、胃肠道和神经系统在内的多个系统受到影响。

结论

推测 COVID-19 在临床环境中可能会出现不同的表现,临床医生应更加谨慎,以免错过 COVID-19 感染的嵌合特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5454/8981785/67939cc476c0/12902_2022_979_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5454/8981785/67939cc476c0/12902_2022_979_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5454/8981785/67939cc476c0/12902_2022_979_Fig1_HTML.jpg

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