Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San Ming District, Kaohsiung, Taiwan.
Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San Ming District, Kaohsiung, Taiwan; Department of Pediatrics, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, San Ming District, Kaohsiung, Taiwan.
Pediatr Neonatol. 2022 Jul;63(4):341-347. doi: 10.1016/j.pedneo.2022.02.002. Epub 2022 Mar 16.
Respiratory distress syndrome (RDS) is the major cause of respiratory failure in preterm infants due to immature lung development and surfactant deficiency. Although the concepts and methods of managing respiratory problems in neonates have changed continuously, determining appropriate respiratory treatment with minimal ventilation-induced lung injury and complications is crucially important. This review summarizes neonatal respiratory therapy's advances and available strategies (i.e., exogenous surfactant therapy, noninvasive ventilation, and different ventilation modes), focusing on RDS management.
呼吸窘迫综合征(RDS)是早产儿呼吸衰竭的主要原因,这是由于肺发育不成熟和表面活性物质缺乏所致。尽管新生儿呼吸问题的处理理念和方法不断变化,但确定适当的呼吸治疗方案,以尽量减少通气引起的肺损伤和并发症至关重要。本综述总结了新生儿呼吸治疗的进展和现有策略(即外源性表面活性物质治疗、无创通气和不同的通气模式),重点介绍 RDS 的管理。