Barter J F, Orr J W, Hatch K D, Shingleton H M
South Med J. 1986 Dec;79(12):1531-4. doi: 10.1097/00007611-198612000-00016.
Several decades ago, diethylstilbestrol (DES) was considered efficacious in improving pregnancy outcome. Later data did not support this, and the exposed mothers and offspring have suffered from a variety of problems attributed to the drug. Knowledge of these problems is essential in dealing with these patients.
几十年前，己烯雌酚（DES）被认为在改善妊娠结局方面有效。后来的数据并不支持这一点，且接触过该药物的母亲和后代出现了各种与该药物有关的问题。了解这些问题对于治疗这些患者至关重要。
