Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan.
Department of Gastroenterology, Nippon Medical School, Tokyo, Japan.
Cancer Rep (Hoboken). 2023 Jan;6(1):e1619. doi: 10.1002/cnr2.1619. Epub 2022 Apr 5.
High-resolution manometry, which measures esophageal luminal pressure changes after swallowing, could shed more light on food-transport dynamics after pharyngeal/esophageal reconstruction. This prospective cohort study assessed the influence of two head-and-neck and esophageal tumor-resection and reconstruction approaches on esophageal pressure.
The cohort consisted of 17 patients who underwent esophageal/pharyngeal resection/reconstruction for cancer and then participated in postoperative high-resolution manometry. Five healthy controls also underwent manometry for comparison.
Partial pharyngectomy with patch grafts associated with smooth and continuous esophageal/pharyngeal movement. By contrast, surgery that removed the thoracic esophagus led to complete loss of peristalsis and poor food transport.
High-resolution manometry effectively characterized the changes in food-transport dynamics caused by pharyngeal/esophageal resection/reconstruction. These findings suggest that continuous and smooth movement of the pharynx and esophagus is important for swallowing and high resolution manometry could be useful in patients after pharyngeal/esophageal resection/reconstruction.
高分辨率测压法可测量吞咽后食管腔内压力变化，可为咽/食管重建后的食物传输动力学提供更多信息。本前瞻性队列研究评估了两种头颈部和食管肿瘤切除及重建方法对食管压力的影响。
该队列包括 17 名因癌症而行食管/咽切除术和重建术的患者，并在术后接受高分辨率测压检查。另外 5 名健康对照者也接受了测压检查作为对照。
带补片的部分咽切除术与食管/咽的平滑连续运动相关。相比之下，切除胸段食管的手术导致了蠕动的完全丧失和食物传输不良。
高分辨率测压法可有效描述咽/食管切除/重建引起的食物传输动力学变化。这些发现表明咽和食管的连续平滑运动对吞咽很重要，高分辨率测压法可能对咽/食管切除/重建后的患者有用。
