胆囊小细胞癌：一种罕见的组织学类型。

Small cell carcinoma of gall bladder: An uncommon histologic entity.

作者信息

Gupta Amit, Anjum Rohik, Mani Rishit, Kumar Navin, Mehan Anoushika, Gupta Sweety, Chowdhury Nilotpal, Kumar Utkarsh

机构信息

Department of Surgery, All India Institute of Medical Sciences, Rishikesh, India.

Department of Surgery All India Institute Of Medical Sciences, Rishikesh Uttarakhand, India.

出版信息

Pol Przegl Chir. 2020 Jul 17;93(0):50-53. doi: 10.5604/01.3001.0014.4878.

DOI:10.5604/01.3001.0014.4878

PMID:35384863

Abstract

Introduction: Gall bladder (GB) small cell carcinoma (SCC) comprises 0.5% of all gall bladder cancers. It carries a poor prognosis in view of its aggressive nature. Case report: We here report a case of small cell carcinoma of GB in a female who presented with obstructive jaundice. Examination revealed a hard lump in the right upper abdomen. Tumour markers showed raised CA 19-9. Staging CECT of the thorax and abdomen reported polypoidal enhancing wall thickening of the gall bladder with multiple metastatic deposits close to the pancreatic head encasing the main portal vein and common bile duct. Histopathology report was suggestive of small cell carcinoma, which was confirmed by immunohistochemistry. Patient was referred to the Oncology Department for palliative chemotherapy.

摘要

引言：胆囊小细胞癌占所有胆囊癌的0.5%。鉴于其侵袭性，预后较差。

病例报告：我们在此报告一例女性胆囊小细胞癌，患者表现为梗阻性黄疸。检查发现右上腹有一硬块。肿瘤标志物显示CA 19-9升高。胸部和腹部的分期增强CT报告显示胆囊呈息肉样强化壁增厚，胰头附近有多个转移灶，包绕门静脉主干和胆总管。组织病理学报告提示为小细胞癌，免疫组化确诊。患者被转至肿瘤科进行姑息化疗。