Cell. 2022 Apr 14;185(8):1279-1282. doi: 10.1016/j.cell.2022.03.026. Epub 2022 Apr 5.
A game-changing intervention in the COVID-19 pandemic has been the rapid implementation of highly effective vaccines against SARS-CoV-2. The 2022 Canada Gairdner International Award recognizes Pieter Cullis, Katalin Karikó, and Drew Weissman "for their pioneering work developing nucleoside-modified mRNA and lipid nanoparticle (LNP) drug delivery: the foundational technologies for the highly effective COVID-19 mRNA vaccines." Cell editor Cheri Sirois caught up with Pieter to discuss how a long interest in basic and applied questions in lipid biology led to this fortuitous collaboration. Excerpts of the conversation are presented below.
在新冠疫情中一项改变游戏规则的干预措施是迅速推广针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的高效疫苗。2022年加拿大盖尔德纳国际奖表彰彼得·卡利斯、卡塔琳·卡里科和德鲁·魏斯曼，“表彰他们在开发核苷修饰信使核糖核酸（mRNA）和脂质纳米颗粒（LNP）药物递送方面的开创性工作：这是高效新冠mRNA疫苗的基础技术”。《细胞》杂志编辑谢里·西罗伊斯采访了彼得，讨论他对脂质生物学基础和应用问题的长期兴趣是如何促成这一机缘巧合的合作的。以下是此次访谈的节选内容。
