Hutasoit Charles Martamba, Sinrang Andi Wardihan, Hatta Mochammad, Rasyid Haerani, Lie Hendry
Dept of Urology, Siloam Hospitals Kebon Jeruk, Jl. Perjuangan No.Kav.8, RT14/RW10, Kebon Jeruk, DKI Jakarta, 11530, Indonesia.
Dept of Physiology, Faculty of Medicine, Universitas Hasanuddin, Jl. Sahabat Raya No. 3, Talamanrea Indah, Kota Makassar, Sulawesi Selatan, Indonesia.
Ann Med Surg (Lond). 2022 Jan 25;75:103294. doi: 10.1016/j.amsu.2022.103294. eCollection 2022 Mar.
Bladder obstruction, including due to benign prostate enlargement (BPH), will trigger its anatomy and physiological function changes. Men with BPH have a 6 times higher risk of erectile dysfunction than those without BPH. Morphological and functional changes in subjects with partial bladder outlet obstruction (pBOO) occur differently depending on the duration of pBOO that has been experienced. The underlying pathophysiology of BPH is closely related to erectile dysfunction. Anatomically, functionally, and psychologically changes due to BPH will also have an impact on sexual function. Chronic pBOO causes lower urinary tract symptoms (LUTS) through a complex pathophysiological pathway. LUTS and bladder obstruction can lead to erectile dysfunction. The severity of LUTS and sexual dysfunction is inversely related to the quality of life. The treatment of LUTS symptoms will also enhance sexual function.
膀胱梗阻，包括由良性前列腺增生（BPH）引起的梗阻，会引发其解剖结构和生理功能的改变。患有BPH的男性发生勃起功能障碍的风险比未患BPH的男性高6倍。部分膀胱出口梗阻（pBOO）患者的形态学和功能改变因经历pBOO的持续时间不同而有所差异。BPH的潜在病理生理学与勃起功能障碍密切相关。BPH在解剖学、功能和心理方面所引起的变化也会对性功能产生影响。慢性pBOO通过复杂的病理生理途径导致下尿路症状（LUTS）。LUTS和膀胱梗阻可导致勃起功能障碍。LUTS的严重程度和性功能障碍与生活质量呈负相关。LUTS症状的治疗也会改善性功能。
