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使用羊源强化生物材料对大型腹侧疝缺损进行桥接修复:病例系列

Bridged repair of large ventral hernia defects using an ovine reinforced biologic: A case series.

作者信息

DeNoto George

机构信息

General Surgery Department, St. Francis Hospital, Roslyn, NY, 11576, USA.

出版信息

Ann Med Surg (Lond). 2022 Mar 2;75:103446. doi: 10.1016/j.amsu.2022.103446. eCollection 2022 Mar.

DOI:10.1016/j.amsu.2022.103446
PMID:35386793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8977941/
Abstract

INTRODUCTION

Of all hernia types, large ventral hernias have the most impact on patient quality of life, however they are also the most difficult type of hernia to repair and are associated with high rates of complications. This case series describes repair of large ventral hernias with an ovine reinforced biologic in a complex patient cohort with comorbidities and concomitant procedures.

METHODS

The author performed bridged repair with an ovine reinforced biologic in 19 consecutive high-risk patients over a 5-year period. In all cases the reinforced biologic was used as an underlay.

OUTCOMES

Of the 19 patients, six (32%) experienced a surgical site occurrence including infection, seroma, abscess, fistula, bioloma, or bowel obstruction. Three patients (16%) had recurrences with two out of three of the recurrences occurring within 6 months of surgery.

CONCLUSIONS

Rates of SSO's and recurrences using ovine reinforced tissue matrix (RTM) were in line with or better than other published studies of bridged repair utilizing biologic or synthetic mesh reinforcement. Ovine RTM's should therefore be considered in complex large ventral hernia repairs.

摘要

引言

在所有类型的疝气中,大型腹壁疝对患者生活质量的影响最大,然而,它们也是最难修复的疝气类型,并且并发症发生率很高。本病例系列描述了在患有合并症和伴随手术的复杂患者队列中,使用羊源强化生物材料修复大型腹壁疝的情况。

方法

作者在5年期间对19例连续的高危患者进行了羊源强化生物材料的桥接修复。在所有病例中,强化生物材料均用作衬垫。

结果

19例患者中,6例(32%)发生了手术部位事件,包括感染、血清肿、脓肿、瘘管、生物瘤或肠梗阻。3例患者(16%)出现复发,其中3例中有2例在术后6个月内复发。

结论

使用羊源强化组织基质(RTM)的手术部位事件和复发率与其他发表的关于使用生物或合成网片强化进行桥接修复的研究相当或更好。因此,在复杂的大型腹壁疝修复中应考虑使用羊源RTM。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a9d/8977941/4e372ead5ffa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a9d/8977941/4e372ead5ffa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a9d/8977941/4e372ead5ffa/gr1.jpg

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