Enjamo Melkamu, Deribew Amare, Semagn Selamawit, Mareg Moges
Department of Reproductive Health, School of Public Health, College of Medicine and Health Science, Dilla University, Dilla, Ethiopia.
Departent of Public Health, St. Paul Hospital Millennium Medical College, Nutrition International's Country Director, Addis Ababa, Ethiopia.
Int J Womens Health. 2022 Mar 31;14:455-466. doi: 10.2147/IJWH.S352348. eCollection 2022.
Premature rupture of membrane (PROM) varies from country to country and complicates 4 to 10% of pregnancies worldwide it has an overwhelming effect on maternal and newborn health. Even though many interventions implemented to tackle it, the problem is persisted.
To identify determinants of premature rupture of membrane among pregnant women who have visited labor wards in four hospitals found in Gedeo zone, Southern Ethiopia.
Hospital-based unmatched case-control study was conducted from February to May 2020. Data were collected among 75 cases and 223 controls using face-to-face interviews. Cases and controls were recruited consecutively from pregnant women who have visited the labor ward. Data were entered into Epi-data version 3.1 and analyzed by using SPSS version 20. Bivariable and Multivariable logistic regression was used to check the association between dependent and independent variables, statistically significant association was declared at p-value < 0.05.
A total of 75 cases and 233 controls were enrolled in the study. Hypertension during index pregnancy [AOR = 2.81 (95% CI: 1.09 -7.23)], history of abortion [AOR = 3.7 (95% CI: 1.41-9.73)], history of caesarean section [AOR = 3.46 (95% CI: 1.34-8.9)] and history of PROM [AOR = 4.77 (95% CI: 2.31-9.89)] were associated with premature rupture of membranes.
Hypertension during the index pregnancy, history of abortion, history of PROM, and history of cesarean section has an association with premature rupture of membrane. The result of the study suggests early identification and treatment of abortion, hypertension, and cesarean section in pregnant women mitigates the risk of premature rupture of membrane.
胎膜早破在不同国家存在差异，全球4%至10%的妊娠会并发胎膜早破，这对孕产妇和新生儿健康产生了巨大影响。尽管采取了许多干预措施来解决这一问题，但该问题仍然存在。
确定在埃塞俄比亚南部盖德奥地区四家医院产科病房就诊的孕妇中胎膜早破的决定因素。
2020年2月至5月进行了一项基于医院的非匹配病例对照研究。通过面对面访谈收集了75例病例和223例对照的数据。病例和对照均连续从到产科病房就诊的孕妇中招募。数据录入Epi-data 3.1版本，并使用SPSS 20版本进行分析。采用双变量和多变量逻辑回归来检验自变量和因变量之间的关联，p值<0.05时声明具有统计学意义的关联。
该研究共纳入75例病例和233例对照。本次妊娠期间的高血压[AOR = 2.81（95%CI：1.09 - 7.23）]、流产史[AOR = 3.7（95%CI：1.41 - 9.73）]、剖宫产史[AOR = 3.46（95%CI：1.34 - 8.9）]和胎膜早破史[AOR = 4.77（95%CI：2.31 - 9.89）]与胎膜早破有关。
本次妊娠期间的高血压、流产史、胎膜早破史和剖宫产史与胎膜早破有关。研究结果表明，早期识别和治疗孕妇的流产、高血压和剖宫产可降低胎膜早破的风险。
