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2020 年,在埃塞俄比亚南部的一家三级医院的妇产科病房中,产妇接近死亡的决定因素:一项基于医院的病例对照研究。

Determinants of maternal near miss among women admitted to maternity wards of tertiary hospitals in Southern Ethiopia, 2020: A hospital-based case-control study.

机构信息

Department of Public Health, College of Medicine and Health Sciences, Wachemo University, Hosaena, Southern Ethiopia.

School of Nursing and Midwifery, Faculty of Health Science, Institute of Health, Jimma University, Jimma, Southwest Ethiopia.

出版信息

PLoS One. 2021 May 17;16(5):e0251826. doi: 10.1371/journal.pone.0251826. eCollection 2021.

DOI:10.1371/journal.pone.0251826
PMID:33999941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8128231/
Abstract

BACKGROUND

A maternal near-miss (MNM) refers to when a gravely ill woman survives a complication as a result of the standard of care she receives or by chance during gestation, childbirth, or within 42 days of the termination of pregnancy. Rescuers of near-miss events share several features with mothers who have died and identifying MNM determinants will aid in improving the capacity of the health system to reduce severe maternal morbidity and mortality. Ethiopia is one of the countries in sub-Saharan Africa with high maternal mortality and morbidity, but there is little evidence on determinants of a MNM based on a WHO criteria. Hence, this study aimed at identifying determinants of MNM among women admitted to tertiary hospitals in southern Ethiopia, 2020.

METHODS

A facilities-based unmatched case-control study was conducted in five selected tertiary hospitals found in central southern Ethiopia from February 1 to June 1, 2020. A total of 322 (81 cases and 241 controls) study participants were included in the study. At the time of their discharge, cases were recruited consecutively, while controls were selected using a systematic sampling method. The cases were women admitted to hospitals during pregnancy, childbirth, or 42 days following termination of pregnancy who met at least one of the WHO near-miss criteria. Whereas the controls comprised of women who were admitted during pregnancy, childbirth, or 42 days following termination of pregnancy and discharged without severe obstetric complications. Data collection was conducted using the interviewer-administered structured questionnaire and data abstraction tool. The data was coded and entered into Epi-Data version 3.1 and exported to SPSS version 23 for analysis. Multivariable logistic regression analysis was conducted and determinants of MNM were established at p-value<0.05.

RESULTS

Severe postpartum hemorrhage (50.6%) and sepsis (23.4%) were the most common reasons for admission of cases. Lack of ANC [AOR = 3.25; 95%CI: 2.21,7.69], prior history of Cesarean section [AOR = 3.53; 95%CI:1.79,6.98], delaying more than 60 minute to access final place of care [AOR = 3.21; 95%CI:1.61,6.39], poor practice of Birth preparedness and complication readiness (BPCR) [AOR = 3.31; 95%CI:1.50,7.29], and history of preexisting medical disorders [AOR = 2.79; 95%CI:1.45,5.37] were identified as significantly determinants of maternal near miss.

CONCLUSION AND RECOMMENDATION

Stakeholders need to enhance their efforts for improving access to roads and transportations. Besides, women who have a prior history of Caesarean section, chronic medical conditions, and no ANC need special attention from their families and health care providers to proactively mitigate the occurrence of serious obstetric complications. More attention has to be paid to birth preparedness and complication readiness activities.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/689f/8128231/adfc9d3efd74/pone.0251826.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/689f/8128231/adfc9d3efd74/pone.0251826.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/689f/8128231/adfc9d3efd74/pone.0251826.g001.jpg
摘要

背景

孕产妇near-miss(MNM)是指由于接受的标准护理或妊娠、分娩或终止妊娠后 42 天内的偶然情况,重病妇女得以幸存的情况。near-miss 事件的救援人员与死亡的母亲有一些共同的特征,确定 MNM 的决定因素将有助于提高卫生系统的能力,以减少严重的孕产妇发病率和死亡率。埃塞俄比亚是撒哈拉以南非洲孕产妇死亡率和发病率较高的国家之一,但根据世界卫生组织的标准,几乎没有关于 MNM 决定因素的证据。因此,本研究旨在确定 2020 年在埃塞俄比亚南部接受三级医院治疗的妇女发生 MNM 的决定因素。

方法

这是一项在埃塞俄比亚中南部五个选定的三级医院进行的基于设施的病例对照研究,研究时间为 2020 年 2 月 1 日至 6 月 1 日。共有 322 名(81 例病例和 241 例对照)研究参与者被纳入研究。在出院时,连续招募病例,而对照则使用系统抽样方法选择。病例是在妊娠、分娩或终止妊娠后 42 天内因至少符合一项世界卫生组织 near-miss 标准而住院的妇女。而对照组包括在妊娠、分娩或终止妊娠后 42 天内住院且无严重产科并发症出院的妇女。数据收集使用访谈者管理的结构化问卷和数据提取工具进行。数据被编码并输入 Epi-Data 版本 3.1,并导出到 SPSS 版本 23 进行分析。进行多变量逻辑回归分析,并在 p 值<0.05 时确定 MNM 的决定因素。

结果

严重产后出血(50.6%)和败血症(23.4%)是导致病例入院的最常见原因。缺乏 ANC [AOR=3.25;95%CI:2.21,7.69]、先前有剖宫产史 [AOR=3.53;95%CI:1.79,6.98]、延迟 60 分钟以上才能到达最终护理地点 [AOR=3.21;95%CI:1.61,6.39]、不良的生育准备和并发症准备(BPCR)实践 [AOR=3.31;95%CI:1.50,7.29]以及先前存在的医疗疾病史 [AOR=2.79;95%CI:1.45,5.37]被确定为孕产妇 near miss 的显著决定因素。

结论和建议

利益相关者需要加大努力改善道路和交通条件。此外,有剖宫产史、慢性疾病和无 ANC 的妇女需要得到家人和医疗保健提供者的特别关注,以主动减轻严重产科并发症的发生。需要更加重视生育准备和并发症准备活动。

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