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人类鼻黏膜血流的交感神经源性控制。

Sympathetic neurogenic control of blood flow in human nasal mucosa.

作者信息

Olsson P, Bende M

出版信息

Acta Otolaryngol. 1986 Nov-Dec;102(5-6):482-7. doi: 10.3109/00016488609119434.

DOI:10.3109/00016488609119434
PMID:3538765
Abstract

Nasal mucosal blood flow was investigated in patients undergoing a stellate ganglion blockade. Elimination of the sympathetic neurogenic control did not affect the resting blood flow in the mucosa, as registered with the 133Xe washout technique. This indicates that the basal sympathetic vasoconstrictor activity is low in the mucosal vessels that regulate blood flow. With laser doppler flowmetry, the normal pattern of spontaneous oscillations in blood flow was seen to be altered following stellate ganglion blockade. This suggests that vasomotion in the mucosa is partly dependent on sympathetic neurogenic activity. Furthermore, the decrease in blood flow normally induced by a peripheral cold provocation could not be elicited after the ganglion blockade, which means that the decrease is mediated by sympathetic vasoconstrictor fibres.

摘要

对接受星状神经节阻滞的患者的鼻黏膜血流进行了研究。用¹³³Xe洗脱技术记录发现,消除交感神经源性控制并不影响黏膜的静息血流。这表明在调节血流的黏膜血管中,基础交感缩血管活性较低。使用激光多普勒血流仪观察到,星状神经节阻滞后,血流自发振荡的正常模式发生了改变。这表明黏膜中的血管运动部分依赖于交感神经源性活动。此外,在神经节阻滞后,通常由外周冷刺激引起的血流减少无法诱发,这意味着这种减少是由交感缩血管纤维介导的。

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